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[经闭孔阴道吊带术治疗尿失禁后失败的危险因素]

[Risk factors for failure after transobturator vaginal tape for urinary incontinence].

作者信息

Lorenzo-Gómez M F, Gómez-García A, Padilla-Fernández B, García-Criado F J, Silva-Abuín J M, Mirón-Canelo J A, Urrutia-Avisrror M

机构信息

Servicio y Cátedra de Urología, Hospital Universitario de Salamanca, Universidad de Salamanca, España.

出版信息

Actas Urol Esp. 2011 Sep;35(8):454-8. doi: 10.1016/j.acuro.2011.03.009. Epub 2011 May 6.

Abstract

OBJECTIVE

To identify risk factors leading to treatment failure in a sample of 302 women with stress urinary incontinence (SUI) treated by transobturator vaginal tape (TOT) with a medium follow-up of 4 years (range 1-6).

MATERIAL AND METHODS

A population based cohort study with prospectively data from 302 women, aged 41-81 years underwent TOT between April 2003-November 2010. Data were collected by validated questionnaire on urinary incontinence, the International Consultation on Incontinence Questionnaire - Short Form (ICIQ-SF), and clinical data-records. Continence was achieved in 262 (Group A) and 40 continued with incontinence (Group B). We investigated the relationship between age, SUI evolution time, type and number of childbirths (eutocic, dystocic, nulliparous, multiparous status) and medical and/or surgical backgrounds. The ICIQ-SF questionnaire was used to describe whether the surgery outcomes were successful or not.

RESULTS

Group A were younger (p=0.0001), had less SUI evolution time (p=0.017); more eutocic childbirths (p=0.000018). Group B had more dystocic childbirth (p=0.022), previous tension free vaginal tape (TVT) or TOT (p=0.03.), antidepressant-anxiolytic drugs (p=0.003), antihypertensive drugs (p=0.0005), type 1 diabetes (p=0.02), arterial hypertension (p=0.0007), respiratory diseases (p=0.025). Differences were not found with regard to nulliparous (p=0.701), multiparous status (p=0.42), obesity (p=0.18), intestinal disorders (p=0.59), oophorectomy (p=0.19), caesarean (p=0.17), prolapse surgery (p=0.29), hysterectomy (p=0.57), allergies (p=0.48), arthritis (p=0.22), arthrosis (p=0.44), depression (p=0.74), type 2 diabetes (p=0.44), smoking patterns (p=0.28), fibromyalgia (p=0.47).

CONCLUSIONS

Elderly women, with long evolution SUI, dystocic delivery, previous TVT or TOT appear as independent risk factors associated to TOT failure. These factors may make the indication of another surgical approach recommendable.

摘要

目的

在302例接受经闭孔阴道无张力尿道中段吊带术(TOT)治疗的压力性尿失禁(SUI)女性样本中,确定导致治疗失败的风险因素,中位随访时间为4年(范围1 - 6年)。

材料与方法

一项基于人群的队列研究,前瞻性收集了2003年4月至2010年11月期间接受TOT治疗的302例年龄在41 - 81岁女性的数据。通过关于尿失禁的有效问卷、国际尿失禁咨询委员会简表(ICIQ - SF)以及临床数据记录收集数据。262例(A组)实现了控尿,40例仍存在尿失禁(B组)。我们研究了年龄、SUI病程、分娩类型和次数(顺产、难产、未生育、多产状态)以及医疗和/或手术史之间的关系。ICIQ - SF问卷用于描述手术结果是否成功。

结果

A组年龄更小(p = 0.0001),SUI病程更短(p = 0.017);顺产次数更多(p = 0.000018)。B组难产次数更多(p = 0.022),既往接受过无张力阴道吊带术(TVT)或TOT(p = 0.03),使用抗抑郁 - 抗焦虑药物(p = 0.003),抗高血压药物(p = 0.0005),1型糖尿病(p = 0.02),动脉高血压(p = 0.0007),呼吸系统疾病(p = 0.025)。在未生育(p = 0.701)、多产状态(p = 0.42)、肥胖(p = 0.18)、肠道疾病(p = 0.59)、卵巢切除术(p = 0.19)、剖宫产(p = 0.17)、盆底器官脱垂手术(p = 0.29)、子宫切除术(p = 0.57)、过敏(p = 0.48)、关节炎(p = 0.22)、关节病(p = 0.44)、抑郁症(p = 0.74)、2型糖尿病(p = 0.44)、吸烟模式(p = 0.28)、纤维肌痛(p = 0.47)方面未发现差异。

结论

老年女性、SUI病程长、难产、既往接受过TVT或TOT似乎是与TOT失败相关的独立风险因素。这些因素可能使得推荐采用另一种手术方法。

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