Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA.
Psychosomatics. 2011 May-Jun;52(3):230-6. doi: 10.1016/j.psym.2010.12.009.
Increased cardiovascular morbidity and mortality have been reported across a number of chronic psychiatric illnesses. Interventions to decrease cardiovascular risk have focused on single health behaviors.
To evaluate the co-occurrence of multiple poor health behaviors that increase cardiovascular risk among veterans with psychiatric diagnoses.
Using data from the 1999 Large Health Survey of Veterans (n=501,161), multivariate logistic regression was used to evaluate the associations between current smoking, no regular exercise, and obesity with each of six Axis I diagnoses.
There were statistically increased odds of co-occurrence of obesity, current tobacco use, and no regular exercise among veterans with each of the psychiatric diagnoses, with the exception of drug use disorders (which was not significantly different from 1). The highest odds were among veterans with schizophrenia, PTSD, and bipolar disorder [OR (95% CI) of 1.37 (1.29, 1.45); 1.26 (1.20, 1.32); and 1.19 (1.11, 1.25), respectively]. The OR for depression was not significant after adjustment for medical comorbidity.
Veterans with psychiatric illnesses, and particularly those with schizophrenia, PTSD, and bipolar disorder, are much more likely to have multiple poor health behaviors that increase their cardiovascular risk. Interventions to decrease cardiovascular risk among veterans with serious mental illness need to target multiple health behaviors.
多项慢性精神疾病的心血管发病率和死亡率均有所上升。降低心血管风险的干预措施主要集中在单一的健康行为上。
评估有精神疾病诊断的退伍军人中多种增加心血管风险的不良健康行为的同时发生情况。
利用 1999 年退伍军人大型健康调查的数据(n=501,161),采用多变量逻辑回归评估当前吸烟、无规律运动和肥胖与每一种六种轴 I 诊断之间的关联。
在每一种精神疾病诊断的退伍军人中,肥胖、当前吸烟和无规律运动同时发生的几率均有统计学意义增加,除药物使用障碍外(与 1 无显著差异)。精神分裂症、创伤后应激障碍和双相情感障碍的退伍军人中几率最高[比值比(95%置信区间)分别为 1.37(1.29,1.45)、1.26(1.20,1.32)和 1.19(1.11,1.25)]。在调整了医疗合并症后,抑郁的比值比没有统计学意义。
有精神疾病的退伍军人,尤其是患有精神分裂症、创伤后应激障碍和双相情感障碍的退伍军人,更有可能同时存在多种增加心血管风险的不良健康行为。需要针对严重精神疾病退伍军人的多种健康行为来降低心血管风险。