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诺氟沙星倍半水合物。

Norfloxacin sesquihydrate.

作者信息

Ravindra Nittala V, Panpalia Gopal M, Jagarlapudi A R P Sarma

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2009 Jan 14;65(Pt 2):o303. doi: 10.1107/S160053680900066X.

DOI:10.1107/S160053680900066X
PMID:21581912
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2968347/
Abstract

IN THE CRYSTAL STRUCTURE OF THE TITLE COMPOUND [SYSTEMATIC NAME: 1-ethyl-6-fluoro-4-oxo-7-(piperazin-4-ium-1-yl)-1,4-dihydro-quinoline-3-carboxyl-ate sesquihydrate], C(16)H(18)FN(3)O(3)·1.42H(2)O, N-H⋯O and O-H⋯O hydrogen bonds assemble the mol-ecules in a two-dimensional layered corrugated sheet structure parallel to the b axis. The water mol-ecules are disordered [occupancies 0.741 (11) and 0.259 (11)].

摘要

在标题化合物[系统名称：1-乙基-6-氟-4-氧代-7-(哌嗪-4-鎓-1-基)-1,4-二氢喹啉-3-羧酸酯倍半水合物]，C(16)H(18)FN(3)O(3)·1.42H(2)O的晶体结构中，N-H⋯O和O-H⋯O氢键将分子组装成平行于b轴的二维层状波纹片结构。水分子无序[占有率0.741 (11)和0.259 (11)]。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b60/2968347/db89b3976794/e-65-0o303-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b60/2968347/c7aac8cd7583/e-65-0o303-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b60/2968347/db89b3976794/e-65-0o303-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b60/2968347/c7aac8cd7583/e-65-0o303-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b60/2968347/db89b3976794/e-65-0o303-fig2.jpg

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