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Ep-oxy-cytochalasin H methanol solvate.

作者信息

Li Li-Mei, Liu Yang, Yang Tai, Yu Kai-Bei, Zou Qiang

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2010 Jul 31;66(Pt 8):o2176-7. doi: 10.1107/S1600536810029600.

Abstract

In the title solvate, C(30)H(39)NO(5)·CH(4)O {systematic name: 21-acet-oxy-18,21-dihy-droxy-5,6,16,18-tetra-methyl-10-phenyl-6,7-ep-oxy-[11]cytochalasa-13,19-dien-1-one methanol solvate}, the organic mol-ecule exhibits the tetra-cyclic terpenoid skeleton of cytochalasin, consisting of fused five-, six-, three- and 11-membered rings. The five-membered ring adopts an envelope conformation, while the six-membered ring is in a boat conformation. The ep-oxy O atom on the six-membered ring is pointing away from the five-membered ring. An inter-stitial methanol solvent mol-ecule is hydrogen bonded to the cytochalasin mol-ecules and inter-molecular O-H⋯O and N-H⋯O hydrogen bonds connect the mol-ecules into infinite chains along the (10) direction.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/397b/3007521/9a6b09194bc3/e-66-o2176-fig1.jpg

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