干性年龄相关性黄斑变性的影像学特征
Imaging characteristics of dry age-related macular degeneration.
作者信息
Sohrab Mahsa A, Smith R Theodore, Fawzi Amani A
机构信息
Doheny Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
出版信息
Semin Ophthalmol. 2011 May;26(3):156-66. doi: 10.3109/08820538.2011.570848.
PURPOSE
To review the current literature regarding the imaging characteristics of dry age-related macular degeneration (AMD) lesions, with a special focus on drusen and geographic atrophy imaging. We also explore the role of novel approach of hyperspectral imaging in AMD.
METHODS
Review of current literature as well as findings in a small group of patients imaged with hyperspectral imaging.
RESULTS
The use of optical coherence tomography, and especially fourier-domain devices, has enhanced our ability to classify various lesions of dry AMD. The increasing role of autofluorescence in characterization and prognostication in geographic atrophy is reviewed. The advances made in automated detection and multimodal imaging are highlighted, with their potential to revolutionize this area of research.
CONCLUSIONS
Recent advances in retinal imaging have improved our understanding of the characteristics and prognostication of dry AMD, with an increasing role for multimodal imaging and image correlations. The potential future role of hyperspectral imaging in dry AMD is also presented herein.
目的
回顾当前关于干性年龄相关性黄斑变性（AMD）病变影像学特征的文献，特别关注玻璃膜疣和地图样萎缩的影像学表现。我们还探讨了高光谱成像这种新方法在AMD中的作用。
方法
回顾当前文献以及一小部分接受高光谱成像的患者的检查结果。
结果
光学相干断层扫描技术，尤其是傅里叶域设备的应用，增强了我们对干性AMD各种病变进行分类的能力。本文回顾了自发荧光在地图样萎缩的特征描述和预后评估中日益重要的作用。重点介绍了自动检测和多模态成像方面取得的进展，及其在该研究领域引发变革的潜力。
结论
视网膜成像的最新进展增进了我们对干性AMD特征和预后的理解，多模态成像和图像关联的作用日益凸显。本文还介绍了高光谱成像在干性AMD中未来可能发挥的作用。
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