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18个月时腹腔镜胃束带术与连续胃内球囊置入术结果的比较:一项临床前瞻性研究。

Comparison of results of laparoscopic gastric banding and consecutive intragastric balloon application at 18 months: a clinical prospective study.

作者信息

Peker Yasin, Coskun Halil, Bozkurt Suleyman, Cin Necat, Atak Tuba, Genc Hudai

机构信息

Department of Surgery, Ataturk Training and Research Hospital, Izmir, Turkey.

出版信息

J Laparoendosc Adv Surg Tech A. 2011 Jul-Aug;21(6):471-5. doi: 10.1089/lap.2010.0439. Epub 2011 May 25.

Abstract

BACKGROUND

Obesity is a serious health problem that leads to serious physical and psychological problems. The methods used in treating obesity include diet and behavioral changes, pharmacotherapy, and surgery. Laparoscopic adjustable gastric banding (LAGB) and intragastric balloon (IGB) applications are two of the methods used to treat obesity. The aim of this study was to compare the effects of LAGB with those of two consecutive IGB applications in weight loss management of obese patients.

METHODS

Thirty-two patients (F/M:24/8) admitted in the study were divided into two groups. In the first group of 16 patients, LAGB was performed, and in the other group two consecutive IGBs were applied. Total weight loss, body mass index (BMI), excess weight loss percent (EWL %), and excess body mass index loss percent (EBMIL %) were recorded at months 6, 12, and 18 for both groups.

RESULTS

At the end of the 6th month, BMI values of LAGB and IGB groups were 36.0 and 30.6  kg/m(2), EWL % were 32.3% and 39.3%, and EBMIL % were 36.3% and 47.1%, respectively. The results were similar. At the end of 12 months, median BMI was 36.6  kg/m(2) for LAGB and 27.5  kg/m(2) for IGB (P<.05). The EWL % and EBMIL % at the end of the 12th month were 57% and 70%, which is significant in favor of IGB. The last evaluation was made at the 18th month of applications, and the three parameters for two applications were found to be similar.

CONCLUSIONS

The achieved weight losses at the 6th month were similar for both groups. However, at the 12th month, two consecutive IGB applications were more effective. At the end of the 18th month, the results were again similar. Two consecutive IGB applications may be offered to obese patients who do not feel ready for surgery.

摘要

背景

肥胖是一个严重的健康问题,会导致严重的身体和心理问题。治疗肥胖的方法包括饮食和行为改变、药物治疗以及手术。腹腔镜可调节胃束带术(LAGB)和胃内球囊置入术(IGB)是用于治疗肥胖的两种方法。本研究的目的是比较LAGB与连续两次IGB应用在肥胖患者体重减轻管理方面的效果。

方法

纳入研究的32例患者(女/男:24/8)分为两组。第一组16例患者接受LAGB手术,另一组接受连续两次IGB置入。两组均在第6、12和18个月记录总体重减轻、体重指数(BMI)、超重减轻百分比(EWL%)和超体重指数减轻百分比(EBMIL%)。

结果

在第6个月末,LAGB组和IGB组的BMI值分别为36.0和30.6kg/m²,EWL%分别为32.3%和39.3%,EBMIL%分别为36.3%和47.1%。结果相似。在第12个月末,LAGB组的中位BMI为36.6kg/m²,IGB组为27.5kg/m²(P<0.05)。第12个月末的EWL%和EBMIL%分别为57%和70%,IGB组明显更优。最后一次评估在应用的第18个月进行,发现两次应用的三个参数相似。

结论

两组在第6个月时实现的体重减轻相似。然而,在第12个月时,连续两次IGB应用更有效。在第18个月末,结果再次相似。对于那些尚未准备好接受手术的肥胖患者,可以考虑连续两次IGB应用。

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