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简明认知评估工具在精神分裂症和双相情感障碍患者及健康对照者中的应用:Brief Cognitive Assessment Tool for Schizophrenia (B-CATS) 与 Screen for Cognitive Impairment in Psychiatry (SCIP) 的比较研究

Brief cognitive assessment instruments in schizophrenia and bipolar patients, and healthy control subjects: a comparison study between the Brief Cognitive Assessment Tool for Schizophrenia (B-CATS) and the Screen for Cognitive Impairment in Psychiatry (SCIP).

机构信息

Psychiatric Hospitalization Unit, Hospital Virgen del Camino, Pamplona-Iruña, Spain.

出版信息

Schizophr Res. 2011 Aug;130(1-3):137-42. doi: 10.1016/j.schres.2011.05.020. Epub 2011 Jun 11.

Abstract

Cognitive impairment in schizophrenia and psychosis is ubiquitous and acknowledged as a core feature of clinical expression, pathophysiology, and prediction of functioning. However, assessment of cognitive functioning is excessively time-consuming in routine practice, and brief cognitive instruments specific to psychosis would be of value. Two screening tools have recently been created to address this issue, i.e., the Brief Cognitive Assessment Tool for Schizophrenia (B-CATS) and the Screen for Cognitive Impairment in Psychiatry (SCIP). The aim of this research was to examine the comparative validity of these two brief instruments in relation to a global cognitive score. 161 patients with psychosis (96 patients diagnosed with schizophrenia and 65 patients diagnosed with bipolar disorder) and 76 healthy control subjects were tested with both instruments to examine their concurrent validity relative to a more comprehensive neuropsychological assessment battery. Scores from the B-CATS and the SCIP were highly correlated in the three diagnostic groups, and both scales showed good to excellent concurrent validity relative to a Global Cognitive Composite Score (GCCS) derived from the more comprehensive examination. The SCIP-S showed better predictive value of global cognitive impairment than the B-CATS. Partial and semi-partial correlations showed slightly higher percentages of both shared and unique variance between the SCIP-S and the GCCS than between the B-CATS and the GCCS. Brief instruments for assessing cognition in schizophrenia and bipolar disorders, such as the SCIP-S and B-CATS, seem to be reliable and promising tools for use in routine clinical practice.

摘要

精神分裂症和精神病患者的认知障碍普遍存在,被认为是临床表现、病理生理学和功能预测的核心特征。然而,在常规实践中,认知功能的评估过于耗时,如果有专门针对精神病的简短认知工具,则会很有价值。最近已经创建了两种筛选工具来解决这个问题,即精神分裂症简要认知评估工具 (B-CATS) 和精神病认知障碍筛选工具 (SCIP)。本研究旨在探讨这两种简短工具在与整体认知评分相关方面的比较有效性。161 名精神病患者(96 名精神分裂症患者和 65 名双相情感障碍患者)和 76 名健康对照者接受了这两种工具的测试,以检查它们相对于更全面的神经心理评估工具包的同时有效性。在三个诊断组中,B-CATS 和 SCIP 的得分高度相关,并且相对于更全面的检查得出的全球认知综合评分 (GCCS),这两个量表均显示出良好到极好的同时有效性。SCIP-S 对整体认知障碍的预测价值优于 B-CATS。部分和半部分相关显示,SCIP-S 与 GCCS 之间的共享和独特方差百分比略高于 B-CATS 与 GCCS 之间的百分比。用于评估精神分裂症和双相情感障碍认知的简短工具,如 SCIP-S 和 B-CATS,似乎是可靠且有前途的常规临床实践工具。

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