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高效抗逆转录病毒治疗时代 HIV 阳性女性的避孕选择。

Contraception choices in a cohort of HIV+ women in the era of highly active antiretroviral therapy.

机构信息

Department of Pediatrics, Maternal-Child HIV Program, University of Nevada School of Medicine, Las Vegas, NV 89102, USA.

出版信息

Contraception. 2011 Jul;84(1):94-7. doi: 10.1016/j.contraception.2010.10.012. Epub 2010 Dec 3.

Abstract

BACKGROUND

The study was conducted to determine whether increased desire for fertility coupled with increased awareness of reduction in mother-to-child HIV transmission (MTCT) with increased availability and use of highly active antiretroviral therapy (HAART) has been associated with reduction in use of tubal sterilization as a form of contraception among women infected with HIV.

STUDY DESIGN

One hundred HIV+ women, 18 to 45 years of age, receiving care at university-affiliated HIV facilities between October 2008 and February 2009, were surveyed about their contraceptive knowledge and practices. We performed descriptive analysis of population characteristics to determine contraception choices and fertility desires following initiation of HAART.

RESULTS

The study group was composed of women with median age of 35 years, 55% African American, 18% Caucasians, 19% Hispanic and 8% "other". Most (63%) were single; 36% were married. Contraception choices were condom 61%, injectable contraceptive 7%, pills 6% and only 3% said they used female sterilization. Thirty-four percent of respondents said that their choice of contraception was based primarily on ease of use, 19% said that their choice was primarily based on convenience and only 9% said that their choice was primarily based on provider recommendation. Desire for future childbearing increased to 19% following knowledge that MTCT can be reduced by taking antiretroviral therapy (ARV) and to 22% following initiation of ARV.

CONCLUSIONS

Initiation of ARV and awareness that maternal treatment can reduce MTCT may explain lower use of female sterilization as a form of contraception among a cohort of HIV+ women in the post HAART era.

摘要

背景

本研究旨在确定,随着高效抗逆转录病毒治疗(HAART)的普及和应用,母婴传播(MTCT)率降低的意识增强,生育愿望增强,是否与 HIV 感染妇女中输卵管绝育术作为避孕方法的使用率降低有关。

研究设计

2008 年 10 月至 2009 年 2 月,我们对在大学附属医院接受治疗的 100 名年龄在 18 至 45 岁之间的 HIV 阳性妇女进行了关于避孕知识和实践的调查。我们对人群特征进行了描述性分析,以确定 HAART 起始后避孕选择和生育愿望。

结果

研究组由中位年龄为 35 岁的女性组成,55%为非裔美国人,18%为白种人,19%为西班牙裔,8%为“其他”。大多数(63%)为单身;36%已婚。避孕选择为避孕套 61%、注射避孕药 7%、避孕药 6%,只有 3%的人表示使用女性绝育。34%的受访者表示,他们选择避孕的主要原因是使用方便,19%的人表示主要原因是方便,只有 9%的人表示主要原因是医生建议。在了解到服用抗逆转录病毒药物(ARV)可以降低 MTCT 后,34%的人表示希望未来生育,而在开始服用 ARV 后,这一比例上升至 22%。

结论

在 HAART 后时代,开始服用 ARV 以及认识到母亲治疗可以降低 MTCT,可能解释了 HIV 阳性妇女中使用女性绝育作为避孕方法的比例降低的原因。

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