Department of Physiological Nursing, University of California, San Francisco, California, USA.
J Pain. 2011 Sep;12(9):1004-16. doi: 10.1016/j.jpain.2011.04.002.
Pain is common among people living with HIV/AIDS (PLWHA), but little is known about chronic pain in socioeconomically disadvantaged HIV-infected populations with high rates of substance abuse in the postantiretroviral era. This cross-sectional study describes the occurrence and characteristics of pain in a community-based cohort of 296 indigent PLWHA. Participants completed questionnaires about sociodemographics, substance use, depression, and pain. Cut-point analysis was used to generate categories of pain severity. Of the 270 participants who reported pain or the use of a pain medication in the past week, 8.2% had mild pain, 38.1% had moderate pain, and 53.7% had severe pain. Female sex and less education were associated with more severe pain. Depression was more common among participants with severe pain than among those with mild pain. Increasing pain severity was associated with daily pain and with chronic pain. Over half of the participants reported having a prescription for an opioid analgesic. Findings from this study suggest that chronic pain is a significant problem in this high risk, socioeconomically disadvantaged group of patients with HIV disease and high rates of previous or concurrent use of illicit drugs.
This article presents epidemiological data showing that unrelieved chronic pain is a significant problem for indigent people living with HIV. Participants reported pain severity similar to those with metastatic cancer. Despite high rates of substance use disorders, approximately half received prescriptions for opioid analgesics, although few for long-acting agents.
艾滋病毒/艾滋病(PLWHA)患者普遍存在疼痛,但在后抗逆转录病毒时代,社会经济处于不利地位且滥用物质率高的艾滋病毒感染者人群中,慢性疼痛的情况鲜为人知。本横断面研究描述了 296 名贫困 PLWHA 社区队列中疼痛的发生和特征。参与者完成了关于社会人口统计学、物质使用、抑郁和疼痛的问卷。切点分析用于生成疼痛严重程度类别。在 270 名报告过去一周内有疼痛或使用止痛药的参与者中,8.2%有轻度疼痛,38.1%有中度疼痛,53.7%有重度疼痛。女性和受教育程度较低与更严重的疼痛相关。与轻度疼痛相比,严重疼痛患者中抑郁更为常见。疼痛严重程度增加与每日疼痛和慢性疼痛有关。超过一半的参与者报告有阿片类镇痛药的处方。本研究结果表明,慢性疼痛是这群患有 HIV 疾病且滥用药物既往或同时发生率高的高危、社会经济处于不利地位的患者的一个重大问题。
本文提供了流行病学数据,表明未缓解的慢性疼痛是贫困 HIV 感染者的一个重大问题。参与者报告的疼痛严重程度与转移性癌症患者相似。尽管物质使用障碍的发生率较高,但大约有一半人接受了阿片类镇痛药的处方,尽管长效制剂的处方很少。