Giuffre Jennifer L, Jacobson Nathan A, Rizzo Marco, Shin Alexander Y
Department of Orthopedic Surgery, Division of Hand Surgery, Mayo Clinic, Rochester, MN 55905, USA.
J Hand Surg Am. 2011 Aug;36(8):1273-81. doi: 10.1016/j.jhsa.2011.05.022. Epub 2011 Jun 25.
A septic joint is a cartilage-threatening emergency requiring prompt treatment. The purpose of this study was to examine outcomes of septic arthritis of the metacarpophalangeal and interphalangeal joints.
We performed a retrospective review of patients diagnosed with joint infection between 1976 and 2008. The end point included the number of arthrodeses and amputations performed.
Septic joints were identified in 110 patients. All patients had incision and irrigation and debridement (I and D) of the joint. The infection was successfully treated in 83 of 110 patients. The majority of septic joints (73 of 83 patients) treated successfully with I and D had only a penetrating joint injury. Forty-eight of these patients required more than one I and D to eradicate the infection. The remaining 27 of 110 patients required either arthrodesis (13 patients) or amputation (14 patients) despite I and D. Among the 13 patients requiring arthrodesis, postoperative infection (7 patients) accounted for the majority of septic joints. Of the 14 patients requiring amputation, penetrating joint injury accounted for the majority of septic joints. Overall, those patients requiring more than 3 I and D procedures were at higher risk of arthrodesis or amputation. Increasing comorbidities correlated with worsening outcomes.
Pyarthrosis can often be treated successfully with 1 or more I and D procedures. Despite multiple I and D procedures, 27 patients required either arthrodesis or amputation. The time to diagnosis and treatment, the number of I and D procedures, patient comorbidities, and postoperative infection following non-joint surgery are major factors influencing outcome.
化脓性关节是一种威胁软骨的急症,需要及时治疗。本研究的目的是检查掌指关节和指间关节化脓性关节炎的治疗结果。
我们对1976年至2008年间诊断为关节感染的患者进行了回顾性研究。终点指标包括关节融合术和截肢手术的数量。
110例患者被诊断为化脓性关节。所有患者均接受了关节切开冲洗和清创术(I&D)。110例患者中有83例感染得到成功治疗。经I&D成功治疗的大多数化脓性关节(83例中的73例)仅有穿透性关节损伤。其中48例患者需要进行不止一次I&D以根除感染。110例患者中的其余27例尽管接受了I&D,但仍需要进行关节融合术(13例患者)或截肢手术(14例患者)。在13例需要进行关节融合术的患者中,术后感染(7例患者)占化脓性关节的大多数。在14例需要截肢的患者中,穿透性关节损伤占化脓性关节的大多数。总体而言,那些需要进行超过3次I&D手术的患者进行关节融合术或截肢的风险更高。合并症增加与预后恶化相关。
脓性关节炎通常可以通过1次或多次I&D手术成功治疗。尽管进行了多次I&D手术,但仍有27例患者需要进行关节融合术或截肢手术。诊断和治疗时间、I&D手术次数、患者合并症以及非关节手术后的术后感染是影响预后的主要因素。