Institute of Radiation Physics, University Hospital Center and University of Lausanne, Lausanne, Switzerland.
Pediatr Radiol. 2011 Sep;41(9):1154-64. doi: 10.1007/s00247-011-2146-8. Epub 2011 Jun 30.
Radiation dose exposure is of particular concern in children due to the possible harmful effects of ionizing radiation. The adaptive statistical iterative reconstruction (ASIR) method is a promising new technique that reduces image noise and produces better overall image quality compared with routine-dose contrast-enhanced methods.
To assess the benefits of ASIR on the diagnostic image quality in paediatric cardiac CT examinations.
Four paediatric radiologists based at two major hospitals evaluated ten low-dose paediatric cardiac examinations (80 kVp, CTDI(vol) 4.8-7.9 mGy, DLP 37.1-178.9 mGy·cm). The average age of the cohort studied was 2.6 years (range 1 day to 7 years). Acquisitions were performed on a 64-MDCT scanner. All images were reconstructed at various ASIR percentages (0-100%). For each examination, radiologists scored 19 anatomical structures using the relative visual grading analysis method. To estimate the potential for dose reduction, acquisitions were also performed on a Catphan phantom and a paediatric phantom.
The best image quality for all clinical images was obtained with 20% and 40% ASIR (p < 0.001) whereas with ASIR above 50%, image quality significantly decreased (p < 0.001). With 100% ASIR, a strong noise-free appearance of the structures reduced image conspicuity. A potential for dose reduction of about 36% is predicted for a 2- to 3-year-old child when using 40% ASIR rather than the standard filtered back-projection method.
Reconstruction including 20% to 40% ASIR slightly improved the conspicuity of various paediatric cardiac structures in newborns and children with respect to conventional reconstruction (filtered back-projection) alone.
由于电离辐射可能产生有害影响,儿童的辐射剂量暴露尤其令人关注。适应性统计迭代重建(ASIR)方法是一种很有前途的新技术,与常规剂量增强方法相比,它可以降低图像噪声并产生更好的整体图像质量。
评估 ASIR 对儿科心脏 CT 检查中诊断图像质量的益处。
两位来自两家大医院的儿科放射科医生评估了十项低剂量儿科心脏检查(80 kVp,CTDI(vol)4.8-7.9 mGy,DLP 37.1-178.9 mGy·cm)。研究队列的平均年龄为 2.6 岁(范围为 1 天至 7 岁)。在 64-MDCT 扫描仪上进行所有采集。在各种 ASIR 百分比(0-100%)下对所有图像进行重建。对于每个检查,放射科医生使用相对视觉分级分析方法对 19 个解剖结构进行评分。为了估计减少剂量的潜力,还在 Catphan 体模和儿科体模上进行了采集。
对于所有临床图像,最佳图像质量是在 20%和 40% ASIR 时获得的(p < 0.001),而在 ASIR 高于 50%时,图像质量显著下降(p < 0.001)。在 100% ASIR 时,结构的无噪声外观降低了图像的对比度。当使用 40% ASIR 而不是标准滤波反投影方法时,预计对于 2 至 3 岁的儿童,可以减少约 36%的剂量。
与单独使用常规重建(滤波反投影)相比,包括 20%至 40% ASIR 的重建略微提高了新生儿和儿童各种儿科心脏结构的可见度。