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与足月低出生体重儿相关的母体危险因素:一项匹配病例对照研究。

Maternal risk factors associated with term low birth weight neonates: a matched-pair case control study.

机构信息

Department of Community Medicine, NDMVPS Medical College, Nashik, India.

出版信息

Indian Pediatr. 2012 Jan;49(1):25-8. doi: 10.1007/s13312-012-0010-z. Epub 2011 May 30.

DOI:10.1007/s13312-012-0010-z
PMID:21719926
Abstract

OBJECTIVE

To study maternal risk factors associated with full term low birth weight (LBW) neonates.

DESIGN

Matched pair case control study.

SETTING

Multicenter study including 2 medical colleges and 1 civil hospital, between July 2009 to December 2009.

PATIENTS

Of 2382 neonates screened, 274 full term LBW babies (of 638) and 274 pair matched controls (of 1744) were included in the study. 364 LBW babies were excluded because of premature delivery/gestational age not known (314), unavailability of suitable matched controls (18), and insufficient data (32).

METHODS

Maternal factors including birth spacing, height, pre-delivery weight and pregnancy weight gain, age, parity, educational and economic status, type of family, antenatal care (ANC), maternal exposure to tobacco, hypertension and anemia were studied.

RESULTS

Birth spacing <36 months, maternal height ≤ 145 cm, pre-delivery weight ≤ 55 kg, pregnancy weight gain <6 kg, exposure to tobacco, inadequate antenatal care, maternal hypertension, low socio-economic status, maternal anemia and less maternal education were associated with delivery of a low birth weight infants. Conditional logistic regression analysis showed that significant risk factors associated with low birth weight were inadequate ANC (OR-4.98, 95% CI-2.64 to 9.39), maternal weight before delivery ≤ 55 kg (OR-4.81, 95% CI-2.53 to 9.15) and height ≤ 145 cm (OR-4.13, 95% CI-2.04 to 8.37).

CONCLUSION

Maternal malnutrition, inadequate antenatal care and poor weight gain during pregnancy are significant predictors for delivery of a low birth weight neonate.

摘要

目的

研究与足月低出生体重(LBW)新生儿相关的产妇危险因素。

设计

匹配病例对照研究。

地点

包括 2 所医学院和 1 所综合医院的多中心研究,于 2009 年 7 月至 2009 年 12 月进行。

患者

在筛查的 2382 名新生儿中,纳入 274 名足月 LBW 婴儿(638 名)和 274 名配对对照(1744 名)。364 名 LBW 婴儿因早产/胎龄不详(314 名)、无法获得合适的配对对照(18 名)和数据不足(32 名)而被排除在外。

方法

研究了产妇因素,包括出生间隔、身高、分娩前体重和孕期体重增加、年龄、产次、教育和经济状况、家庭类型、产前保健(ANC)、母亲接触烟草、高血压和贫血。

结果

出生间隔<36 个月、产妇身高≤145cm、分娩前体重≤55kg、孕期体重增加<6kg、接触烟草、产前保健不足、产妇高血压、社会经济地位较低、产妇贫血和产妇教育程度较低与低出生体重儿的分娩有关。条件逻辑回归分析显示,与低出生体重相关的显著危险因素是 ANC 不足(OR-4.98,95%CI-2.64 至 9.39)、分娩前体重≤55kg(OR-4.81,95%CI-2.53 至 9.15)和身高≤145cm(OR-4.13,95%CI-2.04 至 8.37)。

结论

产妇营养不良、产前保健不足和孕期体重增加不良是分娩低出生体重新生儿的重要预测因素。

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