Reis H, Kerker J, Schaefer A, Budde T, Schmid K W, Metz K A
Institut für Pathologie und Neuropathologie, Universitätsklinikum Essen, Hufelandstr. 55, 45122, Essen, Deutschland.
Pathologe. 2011 Nov;32(6):521-3. doi: 10.1007/s00292-011-1461-z.
Heterotopic gastric mucosa is a rare finding in the rectum. Apart from two other hypotheses, a misdifferentiation of entodermal stem cells is the most widely accepted aetiopathogenetic assumption today. Due to acid secretion, the lesions predominantly manifest with hematochezia. Therapeutic options include medicinal therapy and particularly (endoscopic) removal. From the pathologist's point of view a careful evaluation is required also in terms of basically possible dysplastic or malignant changes.
直肠异位胃黏膜是一种罕见的发现。除了其他两种假说外，内胚层干细胞的分化异常是目前最被广泛接受的病因学假设。由于胃酸分泌，这些病变主要表现为便血。治疗选择包括药物治疗，尤其是（内镜）切除。从病理学家的角度来看，还需要仔细评估是否存在基本可能的发育异常或恶性变化。
