Department of Radiation Oncology, University Hospitals Seidman Cancer Center, Cleveland, OH, USA.
Future Oncol. 2011 Jul;7(7):915-25. doi: 10.2217/fon.11.61.
Standard whole-breast irradiation consisting of a dose of 45-50 Gy over 5 weeks with or without the addition of a boost to the tumor bed has equivalent survival to mastectomy and is considered to be the standard of care for most patients with early-stage breast cancer. Newer techniques have been developed to shorten the course of radiation or limit normal tissue exposure in an attempt to increase accessibility to and tolerance of radiation therapy. This article will review some of the newer regimens and techniques for treating early-stage breast cancer after breast-conserving surgery.
标准的全乳照射包括 5 周内给予 45-50 Gy 的剂量,或在肿瘤床处加量照射,其生存率与乳房切除术相当,被认为是大多数早期乳腺癌患者的标准治疗方法。为了提高放疗的可及性和耐受性,已经开发出了一些新的技术来缩短放疗疗程或限制正常组织的暴露。本文将回顾保乳手术后治疗早期乳腺癌的一些新方案和技术。