Unidad de Biotecnología, Centro de Investigación Científica de Yucatán, Calle 43 No. 130 Col. Chuburná de Hidalgo, Mérida, Yucatán, 97200 México.
Nat Prod Res. 2011 Jul;25(12):1185-9. doi: 10.1080/14786419.2010.511215.
The methanolic crude extract from the roots of Jacquinia flammea showed moderate antifungal activity against dermatophytes and very strong antifungal activity against Colletotrichum gloeosporioides. The bioassay-guided purification of the extract, using a combination of vacuum-liquid chromatography and high performance liquid chromatography, allowed the identification of sakurasosaponin as the main metabolite responsible for the antifungal activity.
从火焰Jacquinia 根的甲醇粗提物显示出对皮肤真菌中度抗真菌活性和对炭疽 Colletotrichum 非常强的抗真菌活性。使用真空液相色谱和高效液相色谱相结合的方法对提取物进行生物测定指导纯化,鉴定出樱花皂苷为主要代谢物,负责抗真菌活性。