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微血管减压术:显著的手术原则与技术细节

Microvascular decompression: salient surgical principles and technical nuances.

作者信息

Forbes Jonathan, Cooper Calvin, Jermakowicz Walter, Neimat Joseph, Konrad Peter

机构信息

Department of Neurosurgery, Vanderbilt University Medical Center.

出版信息

J Vis Exp. 2011 Jul 5(53):e2590. doi: 10.3791/2590.

Abstract

Trigeminal neuralgia is a disorder associated with severe episodes of lancinating pain in the distribution of the trigeminal nerve. Previous reports indicate that 80-90% of cases are related to compression of the trigeminal nerve by an adjacent vessel. The majority of patients with trigeminal neuralgia eventually require surgical management in order to achieve remission of symptoms. Surgical options for management include ablative procedures (e.g., radiosurgery, percutaneous radiofrequency lesioning, balloon compression, glycerol rhizolysis, etc.) and microvascular decompression. Ablative procedures fail to address the root cause of the disorder and are less effective at preventing recurrence of symptoms over the long term than microvascular decompression. However, microvascular decompression is inherently more invasive than ablative procedures and is associated with increased surgical risks. Previous studies have demonstrated a correlation between surgeon experience and patient outcome in microvascular decompression. In this series of 59 patients operated on by two neurosurgeons (JSN and PEK) since 2006, 93% of patients demonstrated substantial improvement in their trigeminal neuralgia following the procedure--with follow-up ranging from 6 weeks to 2 years. Moreover, 41 of 66 patients (approximately 64%) have been entirely pain-free following the operation. In this publication, video format is utilized to review the microsurgical pathology of this disorder. Steps of the operative procedure are reviewed and salient principles and technical nuances useful in minimizing complications and maximizing efficacy are discussed.

摘要

三叉神经痛是一种与三叉神经分布区域内严重的刀割样疼痛发作相关的疾病。既往报道表明,80% - 90%的病例与邻近血管对三叉神经的压迫有关。大多数三叉神经痛患者最终需要手术治疗以缓解症状。治疗的手术选择包括毁损性手术(如放射外科、经皮射频毁损、球囊压迫、甘油神经根切断术等)和微血管减压术。毁损性手术未能解决该疾病的根本原因,且从长期来看,在预防症状复发方面比微血管减压术效果更差。然而,微血管减压术本质上比毁损性手术更具侵入性,且手术风险更高。既往研究已证实微血管减压术中外科医生的经验与患者预后之间存在相关性。在本系列自2006年以来由两位神经外科医生(JSN和PEK)手术治疗的59例患者中,93%的患者术后三叉神经痛有显著改善,随访时间为6周至2年。此外,66例患者中有41例(约64%)术后完全无痛。在本出版物中,采用视频形式回顾了该疾病的显微手术病理学。回顾了手术步骤,并讨论了有助于将并发症降至最低并使疗效最大化的重要原则和技术细节。

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