Successful pregnancy in a Swyer syndrome patient with preexisting hypertension.

OBJECTIVE

To report a case of a successful pregnancy and delivery of a patient with 46,XY pure gonadal dysgenesis (Swyer syndrome) and preexisting chronic hypertension who underwent in vitro fertilization (IVF) and embryo transfer (ET).

DESIGN

Case report and review of the literature.

SETTING

2nd Department of Obstetrics and Gynecology, University of Athens, Medical School, "Aretaieion" Hospital. Division of Pediatric-Adolescent Gynecology and Reconstructive Surgery.

PATIENT(S): A 35-year-old woman with Swyer syndrome and chronic idiopathic hypertension.

INTERVENTION(S): Karyotype analysis due to primary amenorrhea; gonadectomy, hormone therapy, investigation of hypertension, IVF using donor oocytes, embryo transfer and caesarean delivery for fetal distress.

MAIN OUTCOME MEASURE(S): Successful pregnancy and live birth.

RESULT(S): We present a rare case of a successful pregnancy of a patient with Swyer syndrome accompanied by idiopathic chronic hypertension.

CONCLUSION(S): A woman with Swyer syndrome, hypoplastic uterus, and chronic hypertension delivered a healthy newborn.