通过金属催化和有机催化的组合实现串联环化-Michael 反应。
Tandem cyclization-Michael reaction by combination of metal- and organocatalysis.
机构信息
Departamento de Química Orgánica (C-1), Facultad de Ciencias, Universidad Autónoma de Madrid, Cantoblanco 28049-Madrid, Spain.
出版信息
J Org Chem. 2011 Sep 2;76(17):7287-93. doi: 10.1021/jo2013077. Epub 2011 Aug 5.
PMID:21786770
Abstract
The use of a catalytic amount of platinum complexes (1 mol %) was found to be compatible with different organocatalysts (DABCO or the Jørgensen-Hayashi catalyst) that were used in the functionalization of various activated methylenes. By this method, a series of lactones with C-3 quaternary centers and substitution at C-5 were prepared.
摘要
使用催化量的铂配合物（1 摩尔%）被发现与不同的有机催化剂（DABCO 或 Jørgensen-Hayashi 催化剂）兼容，这些催化剂用于各种活化亚甲基的官能化。通过这种方法，制备了一系列具有 C-3 季碳原子和 C-5 取代的内酯。
Zotero 插件