Walldorf J, Dollinger M M, Seufferlein T
Klinik und Poliklinik für Innere Medizin I, Universitätsklinikum Halle, Ernst-Grube-Straße 40, 06120, Halle, Deutschland.
Internist (Berl). 2011 Oct;52(10):1178-84. doi: 10.1007/s00108-011-2822-7.
The desire to have children and pregnancy itself are important topics in the treatment of patients under immunosuppression. In this review the risks of frequently prescribed immunosuppressants are discussed regarding the safety of mother and child during and after pregnancy. Knowledge of the specific risks of immunosuppressants in pregnancy is important to balance the therapy between the patients' desire to be treated most effectively and to deliver a healthy child after an uncomplicated pregnancy. Generally, an interdisciplinary approach is advisable in treating and counseling immunosuppressed patients with a desire to have children and during pregnancy.
生育意愿和怀孕本身是免疫抑制患者治疗中的重要话题。在本综述中,讨论了常用免疫抑制剂在孕期及产后对母婴安全的风险。了解免疫抑制剂在孕期的特定风险对于平衡治疗至关重要,既要满足患者最有效治疗的需求,又要确保孕期顺利并产下健康婴儿。一般来说,对于有生育意愿的免疫抑制患者及其孕期治疗,采用多学科方法是可取的。