Mahajan Rajiv, Singh Navyug R, Singh Jaswinder, Dixit Alok, Jain Amit, Gupta Ashwani
Department of Pharmacology, Adesh Institute of Medical Sciences and Research, Bathinda, India.
J Pharm Bioallied Sci. 2010 Apr;2(2):132-6. doi: 10.4103/0975-7406.67008.
In the last 30 years concepts in pharmacology have moved from Essential Medicines (EM) to P-drugs via the Rational Use of Medicines (RUM), but no structured study has evaluated the level of understanding among the working clinicians about these concepts.
The present study was designed to assess the attitude and knowledge of clinical practitioners about the concepts of RUM, EM, P-drugs, and sources of drug-information, across North India.
A cross-sectional study was carried out in and around the teaching hospitals attached to Medical Colleges, enrolling 504 clinicians from six centers across North India to fill-up a questionnaire containing 25 questions.
The results were compiled using percentages and averages. Univariate analysis, which explores each variable in a data set separately, was carried out by using the Fisher's exact test.
Only one-fourth of the participants claimed that they always prescribed Essential Medicine; no one could correctly count the number of drugs / drug combinations in the Indian Essential Drug list; only 15.1% of the clinicians wrote the generic names of drugs on the prescription slip; about one-third of clinicians were not fully aware about the adverse effects, drug interactions, and contraindications of the drugs they prescribed; about 83% of physicians admitted to relying on information from Medical Representatives and an interest in research activities seemed to be lost.
Results show a sorry state of affairs among clinicians, as far as the level of understanding about EM, P-drugs, and RUM is concerned, and it points toward arranging more continuing medical education (CME) for clinicians with regard to these concepts.
在过去30年里,药理学概念已从基本药物(EM)经由合理用药(RUM)发展到精准药物(P - drugs),但尚无结构化研究评估在职临床医生对这些概念的理解程度。
本研究旨在评估印度北部临床医生对合理用药、基本药物、精准药物概念以及药物信息来源的态度和知识。
在医学院附属教学医院及其周边开展了一项横断面研究,招募了来自印度北部六个中心的504名临床医生填写一份包含25个问题的问卷。
结果采用百分比和平均值进行汇总。使用Fisher精确检验进行单变量分析,该分析分别探究数据集中的每个变量。
只有四分之一的参与者声称他们总是开具基本药物;没有人能正确数出印度基本药物清单中的药物/药物组合数量;只有15.1%的临床医生在处方单上写药物通用名;约三分之一的临床医生不完全了解他们所开药物的不良反应、药物相互作用和禁忌症;约83%的医生承认依赖医药代表提供的信息,且似乎对研究活动失去了兴趣。
就对基本药物、精准药物和合理用药的理解水平而言,结果显示临床医生的情况令人遗憾,这表明需要针对这些概念为临床医生安排更多的继续医学教育(CME)。