形态学与感觉树突的功能有什么关系？
How does morphology relate to function in sensory arbors?
机构信息
Department of Neuroscience, Albert Einstein College of Medicine, Bronx, New York 10461, USA.
出版信息
Trends Neurosci. 2011 Sep;34(9):443-51. doi: 10.1016/j.tins.2011.07.004. Epub 2011 Aug 16.
Abstract
Sensory dendrites fall into many different morphological and functional classes. Polymodal nociceptors are one subclass of sensory neurons, which are of particular note owing to their elaborate dendritic arbors. Complex developmental programs are required to form these arbors and there is striking conservation of morphology, function and molecular determinants between vertebrate and invertebrate polymodal nociceptors. Based on these studies, we argue that arbor morphology plays an important role in the function of polymodal nociceptors. Similar associations between form and function might explain the plethora of dendrite morphologies seen among all sensory neurons.
摘要
感觉树突分为许多不同的形态和功能类别。多模态伤害感受器是感觉神经元的一个子类，由于其精细的树突分支而备受关注。形成这些树突分支需要复杂的发育程序，并且在脊椎动物和无脊椎动物的多模态伤害感受器之间，形态、功能和分子决定因素具有惊人的保守性。基于这些研究，我们认为树突形态在多模态伤害感受器的功能中起着重要作用。形态和功能之间的类似关联可能解释了所有感觉神经元中存在的众多树突形态。
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