Mizuno Ju, Morita Shigeho, Hanaue Nobuaki, Hanaoka Kazuo, Yokoyama Takeshi
Department of Anesthesiology, Teikyo University School of Medicine, Tokyo 173-8605.
Masui. 2011 Aug;60(8):908-12.
Intravenous patient-controlled analgesia (IV-PCA) using opioids such as morphine and fentanyl can be an effective analgesic method for post-operative pain that is resistant to conventional administration of narcotic analgesics and nonsteroidal anti-inflammatory drugs, and where epidural block and peripheral nerve block are not feasible. In addition to post-operative pain relief, IV-PCA can facilitate early ambulation, reduce respiratory complications, and increase patient satis-faction. However, respiratory and circulatory depression, and post-operative nausea and vomiting (PONV) often occur as side effects of IV-PCA with opioids. Administration of droperidol can be an effective treatment for PON.
使用吗啡和芬太尼等阿片类药物的静脉自控镇痛(IV-PCA)对于常规使用麻醉性镇痛药和非甾体抗炎药无效且无法进行硬膜外阻滞和外周神经阻滞的术后疼痛而言,可能是一种有效的镇痛方法。除缓解术后疼痛外,IV-PCA还可促进早期活动、减少呼吸并发症并提高患者满意度。然而,使用阿片类药物进行IV-PCA时,呼吸和循环抑制以及术后恶心呕吐(PONV)常作为副作用出现。使用氟哌利多可有效治疗PON。