腹部高加速采集技术的磁共振血管造影增强。
Contrast-enhanced MR angiography of the abdomen with highly accelerated acquisition techniques.
机构信息
Department of Radiology, Mayo Clinic, Opus 2-133, 200 First Street SW, Rochester, MN 55905, USA.
出版信息
Radiology. 2011 Nov;261(2):587-97. doi: 10.1148/radiol.11110242. Epub 2011 Sep 7.
PURPOSE
To demonstrate that highly accelerated (net acceleration factor [R(net)] ≥ 10) acquisition techniques can be used to generate three-dimensional (3D) subsecond timing images, as well as diagnostic-quality high-spatial-resolution contrast material-enhanced (CE) renal magnetic resonance (MR) angiograms with a single split dose of contrast material.
MATERIALS AND METHODS
All studies were approved by the institutional review board and were HIPAA compliant; written consent was obtained from all participants. Twenty-two studies were performed in 10 female volunteers (average age, 47 years; range, 27-62 years) and six patients with renovascular disease (three women; average age, 48 years; range, 37-68 years; three men; average age, 60 years; range, 50-67 years; composite average age, 54 years; range, 38-68 years). The two-part protocol consisted of a low-dose (2 mL contrast material) 3D timing image with approximate 1-second frame time, followed by a high-spatial-resolution (1.0-1.6-mm isotropic voxels) breath-hold 3D renal MR angiogram (18 mL) over the full abdominal field of view. Both acquisitions used two-dimensional (2D) sensitivity encoding acceleration factor (R) of eight and 2D homodyne (HD) acceleration (R(HD)) of 1.4-1.8 for R(net) = R · R(HD) of 10 or higher. Statistical analysis included determination of mean values and standard deviations of image quality scores performed by two experienced reviewers with use of eight evaluation criteria.
RESULTS
The 2-mL 3D time-resolved image successfully portrayed progressive arterial filling in all 22 studies and provided an anatomic overview of the vasculature. Successful timing was also demonstrated in that the renal MR angiogram showed adequate or excellent portrayal of the main renal arteries in 21 of 22 studies.
CONCLUSION
Two-dimensional acceleration techniques with R(net) of 10 or higher can be used in CE MR angiography to acquire (a) a 3D image series with 1-second frame time, allowing accurate bolus timing, and (b) a high-spatial-resolution renal angiogram.
SUPPLEMENTAL MATERIAL
http://radiology.rsna.org/lookup/suppl/doi:10.1148/radiol.11110242/-/DC1.
目的
证明高加速（净加速因子 [R(net)] ≥ 10）采集技术可用于生成三维（3D）亚秒级时相图像，以及单次分割剂量对比剂增强（CE）磁共振（MR）血管造影时具有诊断质量的高空间分辨率对比剂增强（CE）肾 MR 血管造影。
材料与方法
所有研究均经机构审查委员会批准，并符合 HIPAA 规定；所有参与者均签署书面知情同意书。22 项研究在 10 名女性志愿者（平均年龄 47 岁；范围，27-62 岁）和 6 名肾血管疾病患者（3 名女性；平均年龄 48 岁；范围，37-68 岁；3 名男性；平均年龄 60 岁；范围，50-67 岁；平均年龄 54 岁；范围，38-68 岁）中进行。该两部分方案包括使用二维（2D）灵敏度编码加速因子（R）为 8 和二维同态（HD）加速（R(HD)）为 1.4-1.8 的低剂量（2 mL 对比剂）3D 时相图像，具有约 1 秒的帧时间，随后是全腹部视野的高空间分辨率（1.0-1.6-mm 各向同性体素）屏气 3D 肾 MR 血管造影（18 mL）。两种采集均使用二维（2D）净加速因子（R(net)）为 10 或更高的二维（2D）灵敏度编码加速因子（R）和二维同态（HD）加速（R(HD)）的 1.4-1.8。统计分析包括由两位具有丰富经验的审查员使用八项评估标准确定图像质量评分的平均值和标准差。
结果
在 22 项研究中，2 mL 3D 时间分辨图像成功描绘了进行性动脉充盈，并提供了血管解剖的全貌。成功的时相还表明，在 22 项研究中的 21 项中，肾 MR 血管造影显示主肾动脉的描绘充分或优秀。
结论
CE MR 血管造影中 R(net)为 10 或更高的二维加速技术可用于获取（a）具有 1 秒帧时间的 3D 图像序列，从而实现准确的团注时间，和（b）高空间分辨率的肾血管造影。
补充材料
http://radiology.rsna.org/lookup/suppl/doi:10.1148/radiol.11110242/-/DC1.
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