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血管性痴呆:临床与神经放射学相关性

Vascular dementia: clinical and neuroradiological correlation.

作者信息

Racić Dusko, Slankamenac Petar, Vujković Zoran, Miljković Sinisa, Dajić Vlado, Kovacević Aleksandra Dominović

机构信息

Department of Neurology, Clinical Centre Banjaluka, Bosnia and Herzegovina.

出版信息

Med Pregl. 2011 Mar-Apr;64(3-4):152-6. doi: 10.2298/mpns1104152r.

Abstract

All stroke patients admitted to Banjaluka Clinical Centre during one year were evaluated by the standard protocol during the hospitalization and three months after the stroke. It included clinical, functional and neuropsychological examination and neuroimaging. Dementia was diagnosed according to the criteria of National Institute of Neurological Disorders and Stroke-Association Internationale pour la Recherche et l'Enseignement en Neurosciences. Demographic and clinical variables were examined. After the exclusion of the patients who died (n = 139) and those who refused to be interviewed during the 3-month follow up (n = 52) and those with pre-stroke dementia (n = 22), a total of 273 (58.8%) patients underwent neuropsychological examination 3 months after the stroke. Forty-nine (19.52%) of them met the criteria for vascular dementia. The predictors of vascular dementia were age, atrial fibrillation, cognitive and functional impairment on admission and functional outcome, subcortical lacunar infarctions, leukoaraiosis, multiple and bilateral brain lesions. Dementia is frequent after stroke and it cannot be determined by a single factor. A combination of several factors increases the critical threshold for cognitive decline.

摘要

在一年时间里,所有入住巴尼亚卢卡临床中心的中风患者在住院期间以及中风后三个月均按照标准方案接受了评估。评估内容包括临床、功能和神经心理学检查以及神经影像学检查。痴呆症根据美国国立神经疾病与中风研究所 - 国际神经科学研究与教学协会的标准进行诊断。对人口统计学和临床变量进行了检查。在排除死亡患者(n = 139)、在3个月随访期间拒绝接受访谈的患者(n = 52)以及中风前患有痴呆症的患者(n = 22)后,共有273名(58.8%)患者在中风后3个月接受了神经心理学检查。其中49名(19.52%)符合血管性痴呆的标准。血管性痴呆的预测因素包括年龄、心房颤动、入院时的认知和功能障碍以及功能结局、皮质下腔隙性梗死、脑白质疏松症、多发性和双侧脑病变。中风后痴呆症很常见,且无法由单一因素确定。多种因素的组合会增加认知能力下降的临界阈值。

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