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聚醚醚酮(PEEK)牙科植入物:文献综述

PEEK dental implants: a review of the literature.

作者信息

Schwitalla Andreas, Müller Wolf-Dieter

机构信息

1  Department of Oral and Maxillofacial Surgery, Clinical Navigation and Robotics, Charité-Campus Virchow Clinic, Berlin, Germany.

出版信息

J Oral Implantol. 2013 Dec;39(6):743-9. doi: 10.1563/AAID-JOI-D-11-00002. Epub 2011 Sep 9.

Abstract

The insertion of dental implants containing titanium can be associated with various complications (eg, hypersensitivity to titanium). The aim of this article is to evaluate whether there are existing studies reporting on PEEK (polyetheretherketone) as an alternative material for dental implants. A systematic literature search of PubMed until December 2010 yielded 3 articles reporting on dental implants made from PEEK. One article analyzed stress distribution in carbon fiber-reinforced PEEK (CFR-PEEK) dental implants by the 3-dimensional finite element method, demonstrating higher stress peaks due to a reduced stiffness compared to titanium. Two articles reported on investigations in mongrel dogs. The first article compared CFR-PEEK to titanium-coated CFR-PEEK implants, which were inserted into the femurs and evaluated after 4 and 8 weeks. The titanium-coated implants showed significantly higher bone-implant contact (BIC) rates. In a second study, implants of pure PEEK were inserted into the mandibles beside implants made from titanium and zirconia and evaluated after 4 months, where PEEK presented the lowest BIC. The existing articles reporting on PEEK dental implants indicate that PEEK could represent a viable alternative material for dental implants. However, further experimental studies on the chemical modulation of PEEK seem to be necessary, mainly to increase the BIC ratio and to minimize the stress distribution to the peri-implant bone.

摘要

植入含钛牙种植体可能会引发各种并发症(如对钛过敏)。本文旨在评估是否有现有研究报道聚醚醚酮(PEEK)作为牙种植体替代材料的情况。截至2010年12月,对PubMed进行的系统文献检索得到3篇关于PEEK牙种植体的报道。一篇文章通过三维有限元方法分析了碳纤维增强PEEK(CFR-PEEK)牙种植体中的应力分布,结果表明与钛相比,由于刚度降低,其应力峰值更高。两篇文章报道了对杂种犬的研究。第一篇文章将CFR-PEEK与钛涂层CFR-PEEK种植体进行了比较,将它们植入股骨,并在4周和8周后进行评估。钛涂层种植体显示出显著更高的骨-种植体接触(BIC)率。在第二项研究中,将纯PEEK种植体与钛和氧化锆制成的种植体一起植入下颌骨,并在4个月后进行评估,结果显示PEEK的BIC最低。现有关于PEEK牙种植体的文章表明,PEEK可能是牙种植体的一种可行替代材料。然而,似乎有必要对PEEK的化学改性进行进一步的实验研究,主要是为了提高BIC比率并使种植体周围骨的应力分布最小化。

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