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被忽视和新兴的真菌感染:以丁香拟青霉所致拟青霉病为重点,综述透明丝孢霉病的疾病负担、体外抗真菌药敏性和治疗。

Neglected and emerging fungal infections: review of hyalohyphomycosis by Paecilomyces lilacinus focusing in disease burden, in vitro antifungal susceptibility and management.

机构信息

Laboratory of Clinical Immunology, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, Brazil.

出版信息

Microbes Infect. 2012 Jan;14(1):1-8. doi: 10.1016/j.micinf.2011.08.004. Epub 2011 Aug 30.

Abstract

Paecilomyces lilacinus is an emerging pathogenic fungus that can cause different clinical manifestations ranging from cutaneous and sub-cutaneous infections to severe oculomycosis. This review discusses infections caused by P. lilacinus, as well as their symptoms and correlates of immune responses, morphological characteristics of the fungus, therapies, in vitro susceptibility tests, laboratory diagnosis and the experimental models available.

摘要

棘白菌素属是一种新兴的致病性真菌,可引起不同的临床表现,从皮肤和皮下感染到严重的眼内感染。本文综述了棘白菌素属引起的感染,以及它们的症状和免疫反应的相关性、真菌的形态学特征、治疗方法、体外药敏试验、实验室诊断和现有的实验模型。

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