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Prioritizing the repair of DNA damage that is encountered by RNA polymerase.优先修复RNA聚合酶遇到的DNA损伤。
Transcription. 2011 Jul;2(4):168-172. doi: 10.4161/trns.2.4.16146.
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Mechanistic insights in transcription-coupled nucleotide excision repair of ribosomal DNA.转录偶联的核糖体 DNA 核苷酸切除修复的机制见解。
Proc Natl Acad Sci U S A. 2018 Jul 17;115(29):E6770-E6779. doi: 10.1073/pnas.1716581115. Epub 2018 Jul 2.
3
The sensitivity of human fibroblasts to N-acetoxy-2-acetylaminofluorene is determined by the extent of transcription-coupled repair, and/or their capability to counteract RNA synthesis inhibition.人类成纤维细胞对N-乙酰氧基-2-乙酰氨基芴的敏感性取决于转录偶联修复的程度和/或其抵消RNA合成抑制的能力。
Nucleic Acids Res. 1996 Dec 1;24(23):4653-9. doi: 10.1093/nar/24.23.4653.
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Dealing with transcription-blocking DNA damage: Repair mechanisms, RNA polymerase II processing and human disorders.应对转录阻断性DNA损伤：修复机制、RNA聚合酶II加工与人类疾病
DNA Repair (Amst). 2021 Oct;106:103192. doi: 10.1016/j.dnarep.2021.103192. Epub 2021 Jul 26.
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Regulation and rate enhancement during transcription-coupled DNA repair.转录偶联的 DNA 修复过程中的调控和速率增强。
Mol Cell. 2010 Dec 10;40(5):714-24. doi: 10.1016/j.molcel.2010.11.012.
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Base excision repair and nucleotide excision repair contribute to the removal of N-methylpurines from active genes.碱基切除修复和核苷酸切除修复有助于从活性基因中去除N-甲基嘌呤。
DNA Repair (Amst). 2002 Aug 6;1(8):683-96. doi: 10.1016/s1568-7864(02)00075-7.
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Structural basis of DNA lesion recognition for eukaryotic transcription-coupled nucleotide excision repair.真核转录偶联核苷酸切除修复中 DNA 损伤识别的结构基础。
DNA Repair (Amst). 2018 Nov;71:43-55. doi: 10.1016/j.dnarep.2018.08.006. Epub 2018 Aug 23.
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RNA Polymerase-I-Dependent Transcription-coupled Nucleotide Excision Repair of UV-Induced DNA Lesions at Transcription Termination Sites, in Saccharomyces cerevisiae.RNA 聚合酶 I 依赖性转录偶联核苷酸切除修复 UV 诱导的 DNA 损伤在转录终止位点，在酿酒酵母。
Photochem Photobiol. 2017 Jan;93(1):363-374. doi: 10.1111/php.12690. Epub 2017 Jan 23.
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What happens at the lesion does not stay at the lesion: Transcription-coupled nucleotide excision repair and the effects of DNA damage on transcription in cis and trans.病变处发生的事情不会停留在病变处：转录偶联核苷酸切除修复以及 DNA 损伤对顺式和反式转录的影响。
DNA Repair (Amst). 2018 Nov;71:56-68. doi: 10.1016/j.dnarep.2018.08.007. Epub 2018 Aug 23.
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Transcription-coupled nucleotide excision repair of a gene transcribed by bacteriophage T7 RNA polymerase in Escherichia coli.在大肠杆菌中，由噬菌体 T7 RNA 聚合酶转录的基因的转录偶联核苷酸切除修复。
DNA Repair (Amst). 2010 Sep 4;9(9):958-63. doi: 10.1016/j.dnarep.2010.06.007. Epub 2010 Jul 17.
引用本文的文献
1
Dynamics of transcription-coupled repair of cyclobutane pyrimidine dimers and (6-4) photoproducts in .在.中，转录偶联修复环丁烷嘧啶二聚体和（6-4）光产物的动力学。
Proc Natl Acad Sci U S A. 2024 Oct 29;121(44):e2416877121. doi: 10.1073/pnas.2416877121. Epub 2024 Oct 23.
2
Regulation of Transcript Elongation.转录延伸的调控。
Annu Rev Microbiol. 2015;69:49-69. doi: 10.1146/annurev-micro-091014-104047. Epub 2015 Jun 24.
3
UvrD facilitates DNA repair by pulling RNA polymerase backwards.UvrD 通过将 RNA 聚合酶向后拉动来促进 DNA 修复。
Nature. 2014 Jan 16;505(7483):372-7. doi: 10.1038/nature12928. Epub 2014 Jan 8.
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Mfd as a central partner of transcription coupled repair.Mfd作为转录偶联修复的核心伙伴。
Transcription. 2013 May-Jun;4(3):109-13. doi: 10.4161/trns.24934. Epub 2013 May 16.
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Prokaryotic nucleotide excision repair.原核生物核苷酸切除修复。
Cold Spring Harb Perspect Biol. 2013 Mar 1;5(3):a012591. doi: 10.1101/cshperspect.a012591.
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Multipartite control of the DNA translocase, Mfd.多组分调控 DNA 转位酶 Mfd.
Nucleic Acids Res. 2012 Nov 1;40(20):10408-16. doi: 10.1093/nar/gks775. Epub 2012 Aug 16.
本文引用的文献
1
Role of the insertion domain and the zinc-finger motif of Escherichia coli UvrA in damage recognition and ATP hydrolysis.大肠杆菌 UvrA 的插入结构域和锌指模体在损伤识别和 ATP 水解中的作用。
DNA Repair (Amst). 2011 May 5;10(5):483-96. doi: 10.1016/j.dnarep.2011.02.002. Epub 2011 Mar 9.
2
Structure of UvrA nucleotide excision repair protein in complex with modified DNA.UvrA 核苷酸切除修复蛋白与修饰 DNA 的复合物结构。
Nat Struct Mol Biol. 2011 Feb;18(2):191-7. doi: 10.1038/nsmb.1973. Epub 2011 Jan 16.
3
Derepression of bacterial transcription-repair coupling factor is associated with a profound conformational change.细菌转录修复偶联因子的去阻遏与深刻的构象变化有关。
J Mol Biol. 2011 Feb 18;406(2):275-84. doi: 10.1016/j.jmb.2010.12.004. Epub 2010 Dec 23.
4
Regulation and rate enhancement during transcription-coupled DNA repair.转录偶联的 DNA 修复过程中的调控和速率增强。
Mol Cell. 2010 Dec 10;40(5):714-24. doi: 10.1016/j.molcel.2010.11.012.
5
Structural basis for the bacterial transcription-repair coupling factor/RNA polymerase interaction.细菌转录-修复偶联因子/RNA 聚合酶相互作用的结构基础。
Nucleic Acids Res. 2010 Dec;38(22):8357-69. doi: 10.1093/nar/gkq692. Epub 2010 Aug 11.
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Roles for the transcription elongation factor NusA in both DNA repair and damage tolerance pathways in Escherichia coli.转录延伸因子 NusA 在大肠杆菌中 DNA 修复和损伤容忍途径中的作用。
Proc Natl Acad Sci U S A. 2010 Aug 31;107(35):15517-22. doi: 10.1073/pnas.1005203107. Epub 2010 Aug 9.
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An N-terminal clamp restrains the motor domains of the bacterial transcription-repair coupling factor Mfd.N 端钳制结构限制了细菌转录修复偶联因子 Mfd 的马达结构域。
Nucleic Acids Res. 2009 Oct;37(18):6042-53. doi: 10.1093/nar/gkp680. Epub 2009 Aug 21.
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Structural and mutational analyses of Deinococcus radiodurans UvrA2 provide insight into DNA binding and damage recognition by UvrAs.耐辐射球菌UvrA2的结构与突变分析为深入了解UvrAs的DNA结合及损伤识别机制提供了线索。
Structure. 2009 Apr 15;17(4):547-58. doi: 10.1016/j.str.2009.02.008.
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A structural model for the damage-sensing complex in bacterial nucleotide excision repair.细菌核苷酸切除修复中损伤感应复合体的结构模型。
J Biol Chem. 2009 May 8;284(19):12837-44. doi: 10.1074/jbc.M900571200. Epub 2009 Mar 13.
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The alkyltransferase-like ybaZ gene product enhances nucleotide excision repair of O(6)-alkylguanine adducts in E. coli.类烷基转移酶ybaZ基因产物增强大肠杆菌中O(6)-烷基鸟嘌呤加合物的核苷酸切除修复。
DNA Repair (Amst). 2009 Jun 4;8(6):697-703. doi: 10.1016/j.dnarep.2009.01.022. Epub 2009 Mar 9.
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