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影响骨质疏松症药物治疗依从性的因素:采用焦点小组方法探讨患者和提供者的观点。

Factors affecting adherence to osteoporosis medications: a focus group approach examining viewpoints of patients and providers.

机构信息

Department of Physical Therapy, Northeastern University, Boston, Massachusetts 02115, USA.

出版信息

J Geriatr Phys Ther. 2011 Apr-Jun;34(2):72-81. doi: 10.1097/JPT.0b013e3181ff03b4.

Abstract

PURPOSE

This qualitative study uses a focus group approach to determine factors influencing adherence to osteoporosis medications among older adults. Thirty-two patients aged 65 to 85 years from the Greater Boston area who were prescribed an osteoporosis medication, 11 general medicine physicians, and 1 nurse practitioner were recruited from Boston-based hospitals affiliated with a large health care system.

METHOD

Focus groups consisting of 6 to 8 subjects including men and women were held separately for providers and patients and conducted until thematic saturation was reached. Responses were obtained from patients and providers during the focus group interviews conducted by a trained focus group moderator. All interviews were audio taped and transcribed by a medical transcriptionist.

RESULTS

According to patients, factors affecting adherence to osteoporosis drugs included lack of knowledge about osteoporosis, dissatisfaction with their doctor visits, side effects, and difficulty or failure to remember instructions for taking medications. Physicians reported lack of patient knowledge, structural barriers, medication side effects, and the inability to track patients' adherence to their medications as barriers to adherence.

CONCLUSION

This study identifies the extent of and reasons for nonadherence as perceived by patients and providers and provides insights into strategies to modify treatment plans to address nonadherence. The results from this study were used to develop a randomized controlled trial to conduct and evaluate patient- and physician-targeted interventions to improve adherence to osteoporosis medications and to examine cost-effectiveness of alternative strategies.

摘要

目的

本定性研究采用焦点小组方法,确定影响老年骨质疏松症患者药物治疗依从性的因素。从隶属于一家大型医疗保健系统的波士顿地区的医院招募了 32 名年龄在 65 岁至 85 岁之间、被开处骨质疏松症药物的患者,11 名普通内科医生和 1 名执业护士。

方法

为患者和医生分别组织了 6 至 8 人的焦点小组,直到达到主题饱和为止。通过一名接受过焦点小组培训的焦点小组主持人在焦点小组访谈中从患者和提供者处获得了答复。所有访谈均进行了录音,并由医疗转录员转录。

结果

根据患者的说法,影响骨质疏松症药物依从性的因素包括缺乏对骨质疏松症的认识、对就诊不满、副作用以及难以或无法记住药物服用说明。医生报告称,患者缺乏知识、结构障碍、药物副作用以及无法跟踪患者对药物的依从性是导致药物依从性差的原因。

结论

本研究确定了患者和提供者感知到的不依从的程度和原因,并提供了有关修改治疗计划以解决不依从问题的策略的见解。本研究的结果被用于开展一项随机对照试验,以开展和评估针对患者和医生的干预措施,以提高骨质疏松症药物的依从性,并研究替代策略的成本效益。

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