用于周围神经阻滞的局部麻醉药添加剂。
Additives to local anesthetics for peripheral nerve blockade.
作者信息
Brummett Chad M, Williams Brian A
机构信息
University of Michigan Health System, Ann Arbor, Michigan, USA.
出版信息
Int Anesthesiol Clin. 2011 Fall;49(4):104-16. doi: 10.1097/AIA.0b013e31820e4a49.
Abstract
Many additives to local anesthetics to prolong the duration of analgesia for peripheral nerve blocks have been studied. In this review, the authors focus on the more commonly described additives, including epinephrine, clonidine, dexmedetomidine, buprenorphine, dexamethasone, tramadol, sodium bicarbonate, and midazolam. While the primary focus of this review is the effect of the additive on the duration of analgesia, neurotoxicity and other safety concerns are also discussed.
摘要
人们已经对许多用于局部麻醉剂的添加剂进行了研究，这些添加剂可延长周围神经阻滞的镇痛持续时间。在本综述中，作者重点关注了更常被描述的添加剂，包括肾上腺素、可乐定、右美托咪定、丁丙诺啡、地塞米松、曲马多、碳酸氢钠和咪达唑仑。虽然本综述的主要重点是添加剂对镇痛持续时间的影响，但也讨论了神经毒性和其他安全问题。
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