Bøhn K A, Friisk C F, Bøe O W, Hysing J
Nybygget legesenter, Jevnaker.
Tidsskr Nor Laegeforen. 1990 May 20;110(13):1693-6.
Effects on serum lipids were examined in a double blind placebo controlled trial including 111 male and females with cholesterol values higher than 7.0 mmol/l. The patients were treated with 6 g Almarin capsules consisting of the highly concentrated fish-oil EPAX 6000 EE in a daily dose corresponding to 2.1 g eicosapentaenoic acid and 1.5 g docosahexaenoic acid, or olive oil control for 12 weeks. We registered the effects on serum triglycerides, total cholesterol and HDL cholesterol. Compared with baseline values a 19.5% median reduction in serum triglycerides could be observed in the n-3 treated group. This reduction was significantly different from control and baseline values. We also observed a favourable trend towards lower total serum cholesterol and higher serum HDL cholesterol.
在一项双盲安慰剂对照试验中,对111名胆固醇值高于7.0 mmol/l的男性和女性的血脂影响进行了研究。患者接受含有高浓缩鱼油EPAX 6000 EE的6克Almarin胶囊治疗,每日剂量相当于2.1克二十碳五烯酸和1.5克二十二碳六烯酸,或接受橄榄油对照治疗,为期12周。我们记录了对血清甘油三酯、总胆固醇和高密度脂蛋白胆固醇的影响。与基线值相比,n-3治疗组血清甘油三酯中位数降低了19.5%。这种降低与对照组和基线值有显著差异。我们还观察到总血清胆固醇降低和血清高密度脂蛋白胆固醇升高的有利趋势。