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创伤后应激综合征和心肌梗死后的健康相关生活质量:8 年随访。

Posttraumatic stress syndromes and health-related quality of life following myocardial infarction: 8-year follow-up.

机构信息

Department of Psychiatry, Columbia University, New York, NY 10032, USA.

出版信息

Gen Hosp Psychiatry. 2011 Nov-Dec;33(6):565-71. doi: 10.1016/j.genhosppsych.2011.08.015. Epub 2011 Sep 28.

Abstract

OBJECTIVES

This study examines the implications of acute stress disorder (ASD), following myocardial infraction (MI), in predicting subsequent posttraumatic stress disorder (PTSD) and impaired quality of life (QoL) 8 years post-MI.

METHODS

MI patients, who were assessed within a week of the MI (Time 1; n=173), were followed up 7 months (Time 2; n=116) and 8 years (Time 3; n=90) post-MI. ASD was assessed at Time 1 and PTSD at Time 2 and Time 3. Health-related QoL was assessed at Time 3.

RESULTS

Unconditional latent class growth models revealed two distinct subpopulations: the recovered/resilient group (94%) demonstrated a decrease from 12.4% of ASD at Time 1 to 6.1% of PTSD at Time 3. Rates of posttraumatic stress syndromes in the chronic group (6%) were 85.3% at Time 1 and 75.7% at Time 3. The two groups differed in pre-MI life events, length of hospitalization, likelihood to have anterior MI, and perceived threat of death. The chronic group reported lower levels of QoL at Time 3.

CONCLUSION

Although most ASD patients demonstrate a trend of recovery, ASD in the immediate aftermath of MI remains a marker of long term adjustment difficulties.

摘要

目的

本研究探讨了心肌梗死(MI)后急性应激障碍(ASD)对随后创伤后应激障碍(PTSD)和生活质量(QoL)受损的预测意义,随访时间为 MI 后 8 年。

方法

MI 患者在 MI 后一周内进行评估(时间 1;n=173),分别在 7 个月(时间 2;n=116)和 8 年(时间 3;n=90)时进行随访。时间 1 评估 ASD,时间 2 和时间 3 评估 PTSD。在时间 3 评估健康相关的 QoL。

结果

无条件潜在类别增长模型显示了两个不同的亚群:恢复/弹性组(94%)显示 ASD 从时间 1 的 12.4%下降到时间 3 的 6.1%。慢性组(6%)的创伤后应激综合征发生率在时间 1 为 85.3%,时间 3 为 75.7%。两组在 MI 前的生活事件、住院时间、前壁 MI 的可能性和对死亡的感知威胁方面存在差异。慢性组在时间 3 报告的 QoL 水平较低。

结论

尽管大多数 ASD 患者表现出恢复的趋势,但 MI 后立即发生的 ASD 仍然是长期适应困难的标志。

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