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下颌骨原始神经外胚层肿瘤的影像学表现:罕见病例报告及文献复习。

Imaging findings in mandibular primitive neuroectodermal tumour: a report of a rare case and review of the literature.

机构信息

Department of Medical Imaging and Intervention, Chang Gung University, Taiwan, Republic of China.

出版信息

Dentomaxillofac Radiol. 2011 Oct;40(7):451-6. doi: 10.1259/dmfr/92169329.

Abstract

Primitive neuroectodermal tumours (PNETs) are aggressive undifferentiated tumours that occur mainly in the central nervous system (CNS). Reviewing the literature, only six cases of primary PNET of the mandible have been reported. These rare tumours are usually overlooked in clinical practice. An 18-year-old woman who presented with dental caries and left cheek swelling was initially diagnosed with facial cellulitis, but the swelling persisted despite adequate intravenous antibiotic therapy. Subsequent ultrasound and MR examinations revealed a tumour originating from the left mandibular ramus. The ultrasonography-guided percutaneous core needle biopsy confirmed the diagnosis of peripheral PNET. The radiographic features of mandibular PNETs are similar to those of PNETs in other regions, except for haemorrhage, necrosis and calcification. In addition, this is the first reported case with sonographic and MR images of this rare tumour, and the first case that was diagnosed based on the ultrasonography-guided percutaneous core needle biopsy. Using these image characteristics, mandibular PNETs can be diagnosed more accurately.

摘要

原始神经外胚层肿瘤(PNETs)是一种侵袭性未分化肿瘤,主要发生在中枢神经系统(CNS)。回顾文献,仅报道了 6 例下颌骨原发性 PNET。这些罕见的肿瘤在临床实践中通常被忽视。一名 18 岁女性因龋齿和左脸颊肿胀就诊,最初被诊断为面部蜂窝织炎,但尽管给予了足够的静脉抗生素治疗,肿胀仍持续存在。随后的超声和磁共振检查显示肿瘤起源于左侧下颌骨支。超声引导下经皮核心针活检证实了外周 PNET 的诊断。下颌骨 PNET 的影像学特征与其他部位的 PNET 相似,除了出血、坏死和钙化。此外,这是首例报道该罕见肿瘤的超声和磁共振图像的病例,也是首例基于超声引导下经皮核心针活检诊断的病例。利用这些影像学特征,可以更准确地诊断下颌骨 PNET。

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