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一项为期12周的双盲研究,比较吡唑拉酸每日两次与消炎痛每日三次治疗强直性脊柱炎患者的疗效、安全性和耐受性。

A 12-week double-blind study of the efficacy, safety and tolerance of pirazolac b.i.d. compared with indomethacin t.i.d. in patients with ankylosing spondylitis.

作者信息

Carcassi C, La Nasa G, Perpignano G

机构信息

Department of Medical Genetics, University of Cagliari, Italy.

出版信息

Drugs Exp Clin Res. 1990;16(1):29-37.

PMID:2198157
Abstract

A 12-week trial was carried out to compare the efficacy of pirazolac (300-600 mg b.i.d.) with that of indomethacin (25-50 mg t.i.d.) in patients with ankylosing spondylitis. A total of 119 patients completed the treatment period, with 32 drop-outs. Both therapies showed significant improvements in clinical symptoms.

摘要

进行了一项为期12周的试验,以比较吡唑拉酸(每日两次,每次300 - 600毫克)与消炎痛(每日三次,每次25 - 50毫克)对强直性脊柱炎患者的疗效。共有119名患者完成了治疗期,32名患者退出。两种疗法在临床症状上均显示出显著改善。

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