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Elucidation of the proton transport mechanism in human carbonic anhydrase II.
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The Active Site of a Prototypical "Rigid" Drug Target is Marked by Extensive Conformational Dynamics.
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Structure and mechanism of copper-carbonic anhydrase II: a nitrite reductase.
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Structural comparison of protiated, H/D-exchanged and deuterated human carbonic anhydrase IX.
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Crystallography and Its Impact on Carbonic Anhydrase Research.
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Active-site solvent replenishment observed during human carbonic anhydrase II catalysis.
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Neutron crystallography aids in drug design.
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本文引用的文献

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Ion-protein coordination: the many faces of a proton.
Nat Chem. 2011 Aug 23;3(9):662-3. doi: 10.1038/nchem.1122.
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Identification of the elusive hydronium ion exchanging roles with a proton in an enzyme at lower pH values.
Angew Chem Int Ed Engl. 2011 Aug 8;50(33):7520-3. doi: 10.1002/anie.201101753. Epub 2011 May 23.
3
Neutron structure of human carbonic anhydrase II: implications for proton transfer.
Biochemistry. 2010 Jan 26;49(3):415-21. doi: 10.1021/bi901995n.
4
Generalized X-ray and neutron crystallographic analysis: more accurate and complete structures for biological macromolecules.
Acta Crystallogr D Biol Crystallogr. 2009 Jun;65(Pt 6):567-73. doi: 10.1107/S0907444909011548. Epub 2009 May 15.
5
Elucidation of the proton transport mechanism in human carbonic anhydrase II.
J Am Chem Soc. 2009 Jun 10;131(22):7598-608. doi: 10.1021/ja8091938.
6
Entrapment of carbon dioxide in the active site of carbonic anhydrase II.
J Biol Chem. 2008 Nov 7;283(45):30766-71. doi: 10.1074/jbc.M805353200. Epub 2008 Sep 2.
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Solvent-mediated proton transfer in catalysis by carbonic anhydrase.
Acc Chem Res. 2007 Aug;40(8):669-75. doi: 10.1021/ar7000588. Epub 2007 Jun 6.

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