Mayo Clinic College of Medicine, Scottsdale, AZ 85258, USA.
Neuromodulation. 2011 Jan;14(1):58-61; discussion 61. doi: 10.1111/j.1525-1403.2010.00307.x. Epub 2010 Nov 4.
Postherpetic neuralgia (PHN) is the most common complication following an acute varicella zoster virus infection. PHN often results in a chronic severe pain condition refractory to conservative pain management treatments. Peripheral nerve stimulation over the affected spinal nerve root may be an effective treatment option for patients with intractable PHN.
To describe a successful case of peripheral nerve stimulation of the second cervical dorsal root ganglion for the treatment of intractable PHN.
An 80-year-old man with a 15-month history of severe PHN was referred to our clinic for pain management. His pain was localized to the left side in the distribution of the C2 dermatome. The patient's pain was unresponsive to comprehensive conventional treatments for PHN including physical therapy, membrane stabilizing medications, opioids, anti-inflammatories, cervical epidural steroid injections, cervical facet joint injections, and dorsal root ganglion blockade with pulsed radiofrequency. After failing to respond to conservative and interventional therapies, a peripheral nerve stimulator trial was conducted for a period of seven days. The lead was placed within the epidural space over the atlanto-axial joint under fluoroscopy to stimulate the left C2 nerve root. This trial resulted in a significant decrease of the patient's pain, and discontinuation of all pain medications.
We describe a case of successful electrode placement at the C2 spinal level for the treatment of refractory PHN.
带状疱疹后神经痛(PHN)是急性水痘-带状疱疹病毒感染后最常见的并发症。PHN 常导致慢性严重疼痛,对保守的疼痛管理治疗有抗性。受累脊神经根周围神经刺激可能是难治性 PHN 患者的有效治疗选择。
描述第二颈椎背根神经节周围神经刺激治疗难治性 PHN 的成功案例。
一名 80 岁男性,PHN 病史 15 个月,严重 PHN 被转诊至我科进行疼痛管理。他的疼痛局限于左侧 C2 皮区分布。患者的疼痛对包括物理治疗、膜稳定剂药物、阿片类药物、抗炎药、颈椎硬膜外类固醇注射、颈椎关节突关节注射以及脉冲射频背根神经节阻滞在内的 PHN 综合常规治疗无反应。在对保守和介入治疗无反应后,进行了为期七天的外周神经刺激试验。在透视引导下,将导线置于寰枢关节的硬膜外腔中以刺激左侧 C2 神经根。该试验导致患者疼痛显著减轻,并停止使用所有止痛药。
我们描述了一例成功将电极放置在 C2 脊柱水平以治疗难治性 PHN 的病例。