MGIT TBc 鉴定试验的性能及 MPT64 检测方法对液体培养物中结核分枝杆菌复合群的鉴定的荟萃分析。
Performance of the MGIT TBc identification test and meta-analysis of MPT64 assays for identification of the Mycobacterium tuberculosis complex in liquid culture.
机构信息
KEMRI-Wellcome Trust Research Programme, P.O. Box 230, 80108 Kilifi, Kenya.
出版信息
J Clin Microbiol. 2011 Dec;49(12):4343-6. doi: 10.1128/JCM.05995-11. Epub 2011 Oct 12.
Abstract
Rapid MPT64-based immunochromatographic tests (MPT64 ICTs) have been developed to detect Mycobacterium tuberculosis complex (MTBC) in culture. We demonstrated the noninferiority of one commercial MTP64 ICT, the MGIT TBc identification (TBcID) test, to GenoType line probe assays for MTBC identification in positive MGIT cultures. Meta-analysis of MPT64 ICT performance for identification of MTBC in liquid culture confirmed similar very high sensitivities and specificities for all three commercial MPT64 assays for which sufficient data were available.
摘要
快速基于 MPT64 的免疫色谱检测法（MPT64 ICT）已经被开发出来，用于检测培养物中的结核分枝杆菌复合群（MTBC）。我们证明了一种商业化的 MTP64 ICT，即 MGIT TBc 鉴定（TBcID）检测法，在阳性 MGIT 培养物中鉴定 MTBC 方面，不劣于 GenoType 线探针分析。对液体培养物中 MTBC 鉴定的 MPT64 ICT 性能的荟萃分析证实，对于所有三种具有足够数据的商业化 MPT64 检测法，其敏感性和特异性都非常高。
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