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奥曲肽在乳糜胸和乳糜腹治疗中的应用。

Use of octreotide in the treatment of chylothorax and chyloperitoneum.

机构信息

Hospital do Coração, Associação do Sanatório Sírio, São Paulo, SP, Brazil.

出版信息

Arq Bras Cardiol. 2011 Aug;97(2):e33-6.

Abstract

Report of three cases of chylothorax and one case of chylous ascites in children who had undergone cardiac surgery with no response to routine clinical treatment, based on fasting and long-term parenteral nutrition. Treatment with octreotide at an initial dose of 1.0 mcg/kg/h was chosen, with a gradual increase of 1.0 mcg/kg/hr/day until a maximum dose of 4.0 mcg/kg/h. All cases had a favorable response, with gradual reduction of drainage output until prognosis improvement with no significant side effects.

摘要

报告了 3 例儿童在心脏手术后出现乳糜胸和 1 例乳糜性腹水,这些病例对常规临床治疗(包括禁食和长期肠外营养)均无反应。选择奥曲肽作为初始剂量为 1.0 mcg/kg/h 的治疗药物,逐渐增加 1.0 mcg/kg/hr/day,直至最大剂量为 4.0 mcg/kg/h。所有病例均有良好的反应,引流逐渐减少,直至预后改善,无明显不良反应。

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