University of Warwick, Warwick Medical School, Division of Metabolic and Vascular Health, Coventry, UK.
J Clin Sleep Med. 2011 Oct 15;7(5 Suppl):S31-3. doi: 10.5664/JCSM.1356.
There is emerging evidence suggesting that disturbances in sleep and sleep disorders play a role in the morbidity of chronic conditions including obesity and hypertension as well as in the development of type-2 diabetes. This brief review examines the role of inflammation in the development of atherosclerosis. Furthermore, it outlines the utility of inflammatory markers and, in particular, adhesion molecules as biomarkers for cardiovascular risk and the factors that affect their level in the circulation. It then discusses the relationship between sleep and markers of inflammation and the role of sleep in immune function.
越来越多的证据表明，睡眠紊乱和睡眠障碍与包括肥胖症和高血压在内的慢性疾病的发病率以及 2 型糖尿病的发生有关。本综述探讨了炎症在动脉粥样硬化形成中的作用。此外，本文概述了炎症标志物的应用价值，尤其是黏附分子作为心血管风险的生物标志物，以及影响其在循环中水平的因素。接着讨论了睡眠与炎症标志物的关系以及睡眠在免疫功能中的作用。
