一个参与异戊烯生物合成的 ispA 突变可以改善大肠杆菌在低温下的生长。
A mutation of ispA that is involved in isoprenoid biogenesis can improve growth of Escherichia coli at low temperatures.
机构信息
Microbial Genetics Laboratory, Genetic Strains Research Center, The Graduate University for Advanced Studies, Sokendai, 1111 Yata, Mishima, Shizuoka 411-8540, Japan.
出版信息
Microbiol Immunol. 2011 Dec;55(12):885-8. doi: 10.1111/j.1348-0421.2011.00391.x.
Abstract
Cells lacking rodZ are defective not only in cell shape, but also in cell growth at low temperatures. Cold-sensitive growth was suppressed by a mutation of ispA without recovery from the round shape, and the mutation improved cell growth of the wild-type at low temperatures.
摘要
rodsZ 缺失的细胞不仅在细胞形态上有缺陷，而且在低温下的细胞生长也有缺陷。ispA 的突变抑制了冷敏感生长，但不能使细胞恢复成圆形，并且该突变提高了野生型细胞在低温下的生长。
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