School of Pharmacy and Health Professions, Creighton University, 2500 California Plaza, Omaha, NE 68178, USA.
Am J Occup Ther. 2011 Sep-Oct;65(5):514-22. doi: 10.5014/ajot.2011.002600.
A systematic review of evidence for the efficacy of environment-based interventions on the affect, behavior, and performance of people with Alzheimer's disease and related dementias was conducted as part of the American Occupational Therapy Association's Evidence-Based Literature Review Project. Thirty-three reports met inclusion criteria. Results suggest that ambient music, aromatherapy, and Snoezelen are modestly effective in reducingagitation but do not consistently have long-term effects. Visually complex environments that give the illusion of barriers deter people from wandering to unsafe places but do not reduce the urge to wander. Evidence that bright light therapy can aid in regulating mood and the sleep-wake cycle and thus help people remain awake during the day is preliminary. Montessori-based programming can be useful in matching activities to the person's remaining skills. Further research is needed to evaluate the long-term effect, contraindications, and best dosages of these interventions.
作为美国职业治疗协会循证文献回顾项目的一部分,对环境干预措施在阿尔茨海默病及相关痴呆患者的情感、行为和表现方面的疗效进行了系统评价。有 33 份报告符合纳入标准。结果表明,环境音乐、芳香疗法和 Snoezelen 在减轻激越方面有一定效果,但没有持续的长期效果。视觉复杂的环境会给人造成障碍的错觉,阻止人们游荡到不安全的地方,但并不能减少游荡的冲动。关于亮光疗法可以帮助调节情绪和睡眠-觉醒周期,从而帮助人们在白天保持清醒的证据尚属初步。基于蒙台梭利的编程可以在活动与患者剩余技能相匹配方面发挥作用。需要进一步研究来评估这些干预措施的长期效果、禁忌症和最佳剂量。