基于功能化 SERS 纳米探针的两种肺癌标志物同步免疫分析检测
Simultaneous immunoassay for the detection of two lung cancer markers using functionalized SERS nanoprobes.
机构信息
Department of Bionano Engineering, Hanyang University, Ansan 426-791, South Korea.
出版信息
Chem Commun (Camb). 2011 Dec 14;47(46):12515-7. doi: 10.1039/c1cc15707h. Epub 2011 Oct 25.
PMID:22027811
Abstract
A quick and reproducible SERS-based immunoassay, using functionalized hollow gold nanospheres and magnetic beads, has been developed. Here, a simultaneous detection of dual cancer markers in blood serum has been achieved under a single excitation wavelength. The accuracy and sensitivity for clinical sera from five patients confirms their diagnostic feasibility.
摘要
一种快速且可重现的基于 SERS 的免疫分析方法，使用功能化的中空金纳米球和磁性珠，已经被开发出来。在这里，在单个激发波长下实现了对血清中双重癌症标志物的同时检测。对来自五名患者的临床血清的准确性和灵敏度的确认证实了其诊断的可行性。
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