Schultheiss T, Kempcke R, Kratzsch F, Eulitz M, Pette M, Reichmann H, Ziemssen T
Klinik für Neurologie, Universitätsklinik Dresden, Fetscherstr. 74, 01307, Dresden, Deutchland.
Nervenarzt. 2012 Apr;83(4):450-7. doi: 10.1007/s00115-011-3376-6.
The increasing therapeutic options for relapsing-remitting multiple sclerosis require a specific treatment and risk management to recognize the individual response as well as potential side effects. To switch from pure MS documentation to MS management by implementing a new multiple sclerosis management and documentation tool may be of importance.
This article presents the novel computer-based patient management system "multiple sclerosis management system 3D" (MSDS 3D).
MSDS 3D allows documentation and visualization of visit schedules and mandatory examinations via defined study modules by integration of data input from patients, attending physicians and MS nurses. It provides forms for the documentation of patient visits as well as clinical and diagnostic findings. Information is collected via interactive touch screens. A specific module which is part of MSDS 3D's current version allows the monthly monitoring of patients under treatment with natalizumab. A checklist covering clinical signs of progressive multifocal leukoencephalopathy (PML) and a detailed questionnaire about the handling of natalizumab in practice have additionally been added.
The MS patient management system MSDS 3D has successfully been implemented and is currently being evaluated in a multi-centre setting. Advanced assessment of patient data may allow improvements in clinical practice and research work. The addition of a checklist and a questionnaire into the natalizumab module may support the recognition of PML during its early, treatable course.
复发缓解型多发性硬化症的治疗选择不断增加,这就需要特定的治疗方法和风险管理,以识别个体反应以及潜在的副作用。通过实施新的多发性硬化症管理和记录工具,从单纯的多发性硬化症记录转变为管理,可能具有重要意义。
本文介绍了新型的基于计算机的患者管理系统“多发性硬化症管理系统3D”(MSDS 3D)。
MSDS 3D通过整合患者、主治医生和多发性硬化症护士的数据输入,允许通过定义的研究模块对就诊时间表和强制性检查进行记录和可视化。它提供了患者就诊以及临床和诊断结果记录的表格。信息通过交互式触摸屏收集。MSDS 3D当前版本的一个特定模块允许每月对接受那他珠单抗治疗的患者进行监测。此外,还增加了一份涵盖进行性多灶性白质脑病(PML)临床体征的检查表和一份关于那他珠单抗实际使用情况的详细问卷。
MS患者管理系统MSDS 3D已成功实施,目前正在多中心环境中进行评估。对患者数据的高级评估可能会改善临床实践和研究工作。在那他珠单抗模块中增加检查表和问卷可能有助于在PML的早期可治疗阶段识别该疾病。