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两种催产素给药方法用于引产对产程各阶段影响的比较研究。

The comparative examination of the effect of two oxytocin administration methods of labor induction on labor duration stages.

作者信息

Bahadoran Parvin, Falahati Juliana, Shahshahan Zahra, Kianpour Maryam

机构信息

Department of Midwifery, Faculty Member, School of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan, Iran.

出版信息

Iran J Nurs Midwifery Res. 2011 Winter;16(1):100-5.

Abstract

BACKGROUND

Oxytocin is the most consumed medication in modern midwifery. The consumption of oxytocin in inducing and strengthening delivery in delivery wards requires an efficient method for making use of this medication with maximum effect and minimum side effects. In this regard, this study has been conducted aiming at comparing the effect of two methods of prescribing oxytocin in inducing delivery on the duration of stages.

METHODS

The present study is of a clinical trial kind with three-blinded parties which was conducted in 2010 on 120 research volunteers who had the inclusion criteria. The samples were randomly assigned into two groups of control and experiment. The data collection means consisted of a questionnaire and a checklist. In order to analyze the data, the SPSS software, version 17, Student T-test and Chi-square test were used.

RESULTS

There was no statistically significant difference between two groups regarding the duration of the first and the first stages and the active phase. The duration of the third stage of delivery was shorter than the group which had stopped using oxytocin at the active phase. There has been no significant difference between the mean of oxytocin dosage from the initiation of the delivery induction till the active phase. The mean of oxytocin dosage has been significantly different between two groups during all stages of delivery so much so that this rate has been lower in the experiment group.

CONCLUSIONS

The results of the data analysis show that the continuation of oxytocin after the active phase not only does not have any advantage regarding the shortening of duration of stages and its cutting but also it leads to a decrease in the consumption dosage of oxytocin in the active phase and the second stage of delivery and on the other hand leads to a decrease in the side effects of the medication on mother and infant.

摘要

背景

缩宫素是现代助产术中使用最多的药物。在产房使用缩宫素引产和增强宫缩需要一种高效的方法,以实现该药物的最大疗效和最小副作用。为此,开展了本研究,旨在比较两种缩宫素给药方法在引产时对产程的影响。

方法

本研究为三盲临床试验,于2010年对120名符合纳入标准的研究志愿者进行。样本被随机分为对照组和试验组。数据收集方式包括问卷和检查表。为分析数据,使用了SPSS 17版软件、学生t检验和卡方检验。

结果

两组在第一产程、第一阶段和活跃期的持续时间上无统计学显著差异。第三产程的持续时间短于在活跃期停止使用缩宫素的组。从引产开始到活跃期,缩宫素剂量的平均值无显著差异。在分娩的所有阶段,两组的缩宫素剂量平均值存在显著差异,以至于试验组的该率较低。

结论

数据分析结果表明,活跃期后继续使用缩宫素不仅在缩短产程方面没有任何优势,而且会导致活跃期和第二产程缩宫素消耗剂量的减少,另一方面会减少药物对母婴的副作用。

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