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[聂鲁达与抗菌药物耐药性]

[Neruda and antimicrobial resistance].

作者信息

Cotera Alejandro

机构信息

Departamento de Medicina, Hospital Clínico de la Universidad de Chile, Santiago de Chile, Chile.

出版信息

Rev Med Chil. 2011 Jul;139(7):955-8. Epub 2011 Sep 16.

Abstract

Antimicrobial resistance has been a problem in medicine, since their incorporation to clinical practice. Numerous papers have been written on the subject. The analysis of two poems by Pablo Neruda "How much does a man live" and "Larynx", included in the volume "Estravagario" and published for the first time in 1957 and 1958, give us an incredible revelation about the concept of resistance. In these poems aureomycin, the first antimicrobial of the family of tetracyclines, was included as a poetic figure and the therapeutic action of antimicrobials was described. "Never so much bugs died I tons of them fell I but the few that remained olive I manifested their perversity". These writings incorporated novel concepts, even for physicians of that time and described the closeness of death that a patient may perceive during the course of a given disease. The capacity of Pablo Neruda to extract the essence of situations and to anticipate to conditions that only years later became clinically relevant problems, is noteworthy.

摘要

自抗菌药物被应用于临床实践以来,耐药性一直是医学领域的一个问题。关于这个主题已经发表了大量论文。对巴勃罗·聂鲁达(Pablo Neruda)的两首诗《一个人能活多久》(How much does a man live)和《喉》(Larynx)的分析,这两首诗收录在《狂热》(Estravagario)一书中,并于1957年和1958年首次出版,它们让我们对耐药性的概念有了惊人的认识。在这些诗中,四环素家族的第一种抗菌药物金霉素被作为一个诗意形象呈现,并描述了抗菌药物的治疗作用。“从未有过这么多虫子死去,成吨的虫子倒下,但剩下的几只像橄榄一样,展现出它们的倔强”。这些作品融入了新颖的概念,即使对于那个时代的医生来说也是如此,并且描述了患者在特定疾病过程中可能感受到的死亡临近感。巴勃罗·聂鲁达提炼情境本质并预见多年后才成为临床相关问题的状况的能力,值得注意。

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