实体器官移植中免疫抑制药物的药理学

Pharmacology of immunosuppressive medications in solid organ transplantation.

作者信息

Schonder Kristine S

机构信息

Department of Pharmacy and Therapeutics University of Pittsburgh School of Pharmacy, 200 Lothrop Street, PFG 01-01-01, Pittsburgh, PA 15213, USA.

出版信息

Crit Care Nurs Clin North Am. 2011 Sep;23(3):405-23. doi: 10.1016/j.ccell.2011.06.001. Epub 2011 Aug 11.

DOI:10.1016/j.ccell.2011.06.001

PMID:22054818

Abstract

The multitude of immunosuppressants available for solid organ transplantation allows for many combinations of immunosuppressive therapies that can be tailored to a patient’s specific lifestyle and immunosuppression needs. Newer agents currently being studied offer even more possibilities for the future to further reduce the incidence of acute rejection and prolong graft and patient survival.

摘要

可用于实体器官移植的免疫抑制剂种类繁多，这使得免疫抑制疗法有多种组合方式，能够根据患者的特定生活方式和免疫抑制需求进行定制。目前正在研究的新型药物为未来进一步降低急性排斥反应的发生率、延长移植物和患者的生存期提供了更多可能性。