盐酸N-甲基-L-亮氨酰-L-亮氨酸一水合物
N-Methyl-l-leucyl-l-leucine hydro-chloride monohydrate.
作者信息
Lu Tao, Xu Mu-Wu, Liao Xiao-Jian, Xu Shi-Hai
出版信息
Acta Crystallogr Sect E Struct Rep Online. 2011 Sep 1;67(Pt 9):o2394. doi: 10.1107/S1600536811031126. Epub 2011 Aug 27.
In the title compound C(13)H(27)N(2)O(3) (+)·Cl(-)·H(2)O, obtained by deprotecting the amino and carboxyl groups of an inter-mediate in the synthesis of the cyclic penta-peptide Galaxamide, a number of hydrogen-bonding inter-actions occur including aminium N-H⋯Cl, amide-carboxyl N-H⋯O, water O-H⋯Cl and carbox-yl-water O-H⋯O associations. The aminium N-H⋯Cl⋯H-N bridging extensions give rise to zigzag chains extending along the a axis, the overall two-dimensional structure lying in the (110) plane.
在通过对环状五肽加拉沙胺合成中间体的氨基和羧基进行脱保护而获得的标题化合物C(13)H(27)N(2)O(3)(+)·Cl(-)·H(2)O中，存在多种氢键相互作用，包括铵基N-H⋯Cl、酰胺-羧基N-H⋯O、水O-H⋯Cl和羧基-水O-H⋯O缔合。铵基N-H⋯Cl⋯H-N桥连延伸形成了沿a轴延伸的锯齿链，整体二维结构位于(110)平面内。
Zotero 插件