College of Medicine, Winthrop Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA.
Endocr Pract. 2012 Jan-Feb;18(1):e1-4. doi: 10.4158/EP11253.CR.
We present a case of papillary thyroid carcinoma arising from struma ovarii treated erroneously as ovarian adenocarcinoma for more than 3 years.
We report clinical, surgical, laboratory, and imaging findings of the study patient and review the relevant literature.
A 64-year-old woman was treated for ovarian adenocarcinoma for more than 3 years before it was determined that she likely had papillary thyroid carcinoma arising from struma ovarii. This is the first reported case of thyroid carcinoma arising from struma ovarii in a patient with a history of bilateral salpingo-oophorectomy. Possible etiologies include residual ovarian tissue after oophorectomy, ectopic thyroid, or metastatic thyroid cancer.
It is important to include struma ovarii and thyroid carcinoma arising from struma ovarii in the differential diagnosis, even with a history of bilateral salpingo-oophorectomy. This case emphasizes the importance of effective communication among the pathologist, oncologist, and surgeon to ensure timely initiation of appropriate therapy and reduced patient morbidity.
我们报告了一例起源于卵巢甲状腺肿的甲状腺乳头状癌病例,该病例在超过 3 年的时间里被误诊为卵巢腺癌。
我们报告了研究患者的临床、手术、实验室和影像学发现,并复习了相关文献。
一名 64 岁女性因卵巢腺癌接受了超过 3 年的治疗,之后才确定她可能患有起源于卵巢甲状腺肿的甲状腺乳头状癌。这是首例双侧输卵管卵巢切除术史患者发生起源于卵巢甲状腺肿的甲状腺癌的报道。可能的病因包括卵巢切除术后残留的卵巢组织、异位甲状腺或转移性甲状腺癌。
即使有双侧输卵管卵巢切除术史,也应将卵巢甲状腺肿和起源于卵巢甲状腺肿的甲状腺癌纳入鉴别诊断,这一点很重要。本病例强调了病理学家、肿瘤学家和外科医生之间有效沟通的重要性,以确保及时开始进行适当的治疗,降低患者的发病率。