基于氧化石墨烯的双输出荧光 DNA 逻辑门设计及银离子和半胱氨酸的检测
Design of a dual-output fluorescent DNA logic gate and detection of silver ions and cysteine based on graphene oxide.
机构信息
Key Laboratory on Luminescence and Real-Time Analysis, Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China.
出版信息
Chem Commun (Camb). 2012 Jan 4;48(1):82-4. doi: 10.1039/c1cc15449d. Epub 2011 Nov 8.
PMID:22068750
Abstract
In the presence of graphene oxide, upon formation of cytosine-Ag-cytosine the fluorescence wavelength of FAM-labeled DNA exhibited a red shift, and its intensity significantly increased. A novel fluorescent DNA sensor for Ag(+) and cysteine detection, and a dual-output fluorescent DNA INHIBIT logic gate are designed.
摘要
在氧化石墨烯存在的情况下，当胞嘧啶-银-胞嘧啶形成时，FAM 标记的 DNA 的荧光波长发生红移，其强度显著增加。设计了一种用于检测 Ag(+)和半胱氨酸的新型荧光 DNA 传感器，以及一种双输出荧光 DNA 抑制逻辑门。
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