Deopujari C E, Kumar Ashish, Karmarkar V S, Biyani N K, Mhatre M, Shah N J
Department of Neurosurgery, Bombay Hospital Institute of Medical Sciences, Mumbai, India.
J Pediatr Neurosci. 2011 Oct;6(Suppl 1):S46-55. doi: 10.4103/1817-1745.85710.
Pediatric brain tumors have always been challenging as well as intriguing in their anatomical, surgical, and postsurgical management-related issues. They are a heterogeneous set of pathologies involving different age groups in childhood and also differ widely from their adult counterparts as far as adjuvant therapies are concerned. Though neurosurgeons across the world are radical in surgery for most of the pediatric tumors, it can often be at the cost of future quality of life in suprasellar tumors. As the time has gone by, the pendulum has swung toward rather conservative and maximal safe surgical resections with adjuvant therapies coming to the forefront. Hence, the aim is to achieve a good quality of life for these children along with a control of tumor growth (rather than cure) and to again tackle the tumors, if required, once these children reach adolescence or adulthood. We have reviewed the literature for different pediatric suprasellar tumors and discussed their current management giving our perspective with illustrative cases.
小儿脑肿瘤在其解剖、手术及术后管理相关问题上一直既具有挑战性又引人入胜。它们是一组异质性的病变,涉及儿童的不同年龄组,并且就辅助治疗而言,与成人脑肿瘤也有很大差异。尽管世界各地的神经外科医生对大多数小儿肿瘤的手术都很激进,但对于鞍上肿瘤,这往往会以牺牲未来生活质量为代价。随着时间的推移,钟摆已转向更为保守和最大程度安全的手术切除,辅助治疗成为前沿。因此,目标是在控制肿瘤生长(而非治愈)的同时,为这些儿童实现良好的生活质量,并在这些儿童进入青春期或成年期后,如果需要,再次应对肿瘤。我们回顾了不同小儿鞍上肿瘤的文献,并结合实例讨论了它们目前的治疗方法,并给出了我们的观点。