Department of Dermatology, University of California at Davis Medical Center, Sacramento, California, USA. 95816
Dermatol Surg. 2011 Oct;37(10):1412-6. doi: 10.1111/j.1524-4725.2011.02138.x. Epub 2011 Aug 23.
Critical to the accuracy of Mohs surgery is the ability to maintain proper orientation of excised tissue with respect to the surrounding skin. Several techniques have been described for maintaining this orientation, although no prior investigations directly compare these techniques.
To compare the incidence of tissue orientation loss resulting from inability to identify skin score marks with that occurring from failure to identify marks made using a gentian violet marker during Mohs micrographic surgery (MMS). We also sought to determine the incidence of scars resulting from skin scoring.
Patients undergoing MMS were prospectively randomized to have their tissue margins oriented using light scoring using a scalpel versus marking them using a gentian violet marker. Incidence of scoring scars and tissue orientation loss were the primary outcome measures.
Data were analyzed for 101 tumors. There were no instances of tissue orientation loss in the scalpel or marker arms, nor were there any visible score mark scars at follow-up.
Incidence of excessive scars resulting from lightly scored tissue or loss of tissue orientation caused by lost gentian violet markings appears to be low. Both methods worked well within the confines of this study.
对于 Mohs 手术的准确性来说,至关重要的是能够正确保持切除组织相对于周围皮肤的方位。尽管已经有几种技术被描述用于保持这种方位,但尚无先前的研究直接比较这些技术。
比较因无法识别皮肤评分标记而导致组织方位丢失的发生率,以及因未能识别 Mohs 显微外科手术 (MMS) 中使用龙胆紫标记物所做标记而导致的组织方位丢失的发生率。我们还试图确定因皮肤评分而导致的疤痕发生率。
前瞻性随机选择接受 MMS 的患者,将其组织边缘用光刀划线,或使用龙胆紫标记物进行标记。评分疤痕和组织方位丢失的发生率是主要的观察指标。
对 101 个肿瘤进行了数据分析。在手术刀或标记物臂中均未发生组织方位丢失,也未在随访时发现可见的评分标记疤痕。
轻度划线组织导致的过度疤痕发生率或因龙胆紫标记丢失而导致的组织方位丢失似乎很低。这两种方法在本研究范围内都效果良好。